Examination of 4379 routine urinalysis specimens with dipsticks sensitive to ascorbic acid showed that 22.8% were positive specimens. The mean urinary vitamin C concentration in this population was 2120 mumol/L. There was a high rate of false-negative dipstick results for hemoglobin in patients with vitamin C in the urine. The highest false-negative rates were observed in urine samples containi...

BACKGROUND The urine dipstick is widely used as an initial screening tool for the evaluation of proteinuria; however, its diagnostic accuracy has not yet been sufficiently evaluated. Therefore, we evaluated its diagnostic accuracy using spot urine albumin/creatinine ratio (ACR) and total protein/creatinine ratio (PCR) in proteinuria. METHODS Using PCR ≥0.2 g/g or ≥0.5 g/g and ACR ≥300 mg/g or...

have shown that omitting microscopy exams results in missed diagnosis, which of course causes repeated specimen collection and additional laboratory testing. A study authored by Nancy Brunzel and Diane Berry analyzing 709 routine specimens revealed reflexing to microscopy resulted in one in four patient samples being overlooked for pathological conditions. The authors reported the negative pred...

The changes in some serum and urine biochemical parameters in Escherichia coli infected premenopausal and postmenopausal patients were studied. Blood specimens as well as early morning midstream urine specimens were collected from forty premenopausal patients aged 13-15 years, forty postmenopausal patients aged 45-60 years and twenty control subjects with no evidence of Escherichia coli infecti...

OBJECTIVE To compare the effectiveness, benefits, and costs of two asymptomatic bacteriuria screening and treatment strategies to prevent pyelonephritis in pregnancy. METHODS A decision analytic model was created to compare strategies based on either 1) a leukocyte esterase-nitrite dipstick, or 2) on urine culture, with a policy of no screening or treatment. A literature search was conducted ...

Recently, the Sysmex UF-100 flow cytometer was developed to automate urinalysis. We compared UF-100 test results with those of an automated dipstick reader. A cross-check of UF-100, dipstick, and microscopic sediment data was performed in 1001 urine samples. Good agreements (P <0.001) were obtained between UF-100 and dipstick data for erythrocytes (r = 0.636) and leukocytes (r = 0.785). Even in...

BACKGROUND & OBJECTIVES Presence of proteinuria is considered as an early marker of an increased risk of progressive kidney disease. Angiotensin converting enzyme (ACE) inhibitors (ACEi) and angiotensin II receptor blockers (ARB) treatment to persons with proteinuria and chronic kidney disease has been shown to decrease the progression to endstage renal disease. As the exact prevalence of prote...

22 Objective: To determine how urine dipstick test, edema, and/or excessive weight gain 23 (EWG, defined as ≥ 500 g/week) at antenatal visits predict significant proteinuria 24 (defined as a protein-to-creatinine ratio [P/Cr, mg/mg] ≥ 0.27) and preeclampsia. 25 Methods: Data from 3279 antenatal visits between 30 and 36 weeks of gestation were 26 studied in 783 women with singleton pregnancies. ...

BACKGROUND Nephropathia epidemica (NE) is a mild form of hemorrhagic fever with renal syndrome (HFRS) that is caused by the Puumala virus. Periodic outbreaks have been described in endemic areas, with a substantial number of previously healthy individuals developing acute kidney injury (AKI). There is a considerable diversity in the clinical course of the disease, and few patients require renal...