The P atom in the title compound, C15H18NO3P, is in a distorted tetra-hedral P(O)(O)2N environment; the bond angles at P are in the range 98.16 (6)-115.82 (6)°. In the crystal, adjacent mol-ecules are linked via N-H⋯O=P hydrogen bonds into a chain running parallel to the b axis. The methyl groups are disordered over two sets of sites in a 0.677 (14):0.323 (14) ratio. The crystal studied was a n...

The asymmetric unit of the title compound, C(19)H(18)NO(3)P, contains two independent mol-ecules in which the P atoms are found in slightly distorted tetrahedral environments. In the crystal, pairs of inter-molecular N-H⋯O(P) hydrogen bonds form two independent centrosymmetric dimers.

The title compound, C(19)H(18)NO(3)P, was prepared by the reaction of diphenyl phospho-rochloridate and benzyl-amine. In the crystal structure, mol-ecules are linked via N-H⋯O=P hydrogen bonds into extended chains parallel to the c axis.

We evaluated the in vitro antifungal activity of diphenyl diselenide and ebselen against echinocandin-susceptible and -resistant strains of Candida parapsilosis using the broth microdilution method. Diphenyl diselenide (MIC range =1-8 µg/mL) and ebselen (MIC range =0.25-4 µg/mL) showed in vitro activity against echinocandin-susceptible isolates. However, ebselen also showed the highest antifung...

The heterogeneous electron transfer reduction of the bicyclic endoperoxide 1,4-diphenyl-2,3-dioxabicyclo[2.2.1]hept-5-ene (4) was investigated in N,N-dimethylformamide at a glassy carbon electrode. The endoperoxide reacts by a concerted dissociative ET mechanism resulting in reduction of the O-O bond with an observed peak potential of -1.4 V at 0.2 V s-1. The major product (90% yield) resulting...

Thioredoxin reductase (TrxR) isoforms play important roles in cell physiology, protecting cells against oxidative processes. In addition to its endogenous substrates (Trx isoforms), hepatic TrxR can reduce organic selenium compounds such as ebselen and diphenyl diselenide to their selenol intermediates, which can be involved in their hepatoprotective properties. Taking this into account, the ai...

A Sc complex of (4S,5S)-diphenyl PYBOX 1 was found to serve as a catalyst for the asymmetric conjugate addition reactions between various thiols and 3-crotonoyl-2-oxazolidinone, affording the corresponding adducts in good yields and high enantioselectivies (up to 92% ee). A new improved method for making (4S,5S)-diphenyl PYBOX is presented.

It was found that cesium carbonate has a unique catalytic ability on the reaction of carbonyl compounds with diphenyl diselenide to give the corresponding alpha-phenylseleno carbonyl compounds in moderate to good yields. Similarly, the alpha-phenylthiolation of carbonyl compounds with diphenyl disulfide was promoted by the cesium carbonate catalyst.

BACKGROUND Polybrominated diphenyl ethers (PBDEs) are persistent, bioaccumulative, and endocrine-disrupting chemicals. OBJECTIVES We used handwipes to estimate exposure to PBDEs in house dust among toddlers and examined sex, age, breast-feeding, race, and parents' education as predictors of serum PBDEs. METHODS Eighty-three children from 12 to 36 months of age were enrolled in North Carolin...

The alkoxycarbonylation of trimethylsilylacetylene has been studied in order to develop an atom economic sustainable synthesis 2‐(trimethylsilyl)acrylates, a family valuable intermediates. Pd(OAc) 2 combination with CH 3 SO H and diphenyl‐(pyridin‐2‐yl)phosphine or diphenyl‐(6‐methyl‐pyridin‐2‐yl)phosphine is active catalyst for the reaction affording mixtures sought 2‐(trimethylsilyl)acrylate ...