WSA2 from mycobacteria have recently been shown to have potent biological activity ( I , 2, 5). These adjuvants are nontoxic in vitro and may prove useful in amplification of the immune response. Adam et a!. ( 1) reported that water-soluble fractions that were extracted from the myco bacterial cell walls were nontoxic and were capable of increasing circulating antibodies and of inducing delayed...

The ion permeability of the membrane junctions between Chironomus salivary gland cells is strongly depressed by treatments that are generally known to inhibit energy metabolism. These treatments include prolonged cooling at 6 degrees -8 degrees C, and exposure to dinitrophenol, cyanide, oligomycin, and N-ethylmaleimide. Intracellular injection of ATP appears to prevent depression of junctional ...

The reaction of nitrophenols (picric acid, 2,6-dinitrophenol, and 2,4-dinitrophenol) with divalent metal oxinate (metal = Cu, Co, Ni, Mn, and Zn) produced a type of molecular complex, which comprises two molecules of the metal oxinate and one molecule of the nitrophenol. In the case of the Mg complex the ratio is 1:1. A definite charge-transfer band is detected for the Co(II) complex. A hydroge...

Rabbit lenses incubated in vitro in potassium-free Tyrode's solution for 4 hours accinnulated trace amounts of Rb-86 to a concentration averaging 18 times that of the incubation medium. The uptake of Rb-86 was temperature dependent and required calcium. In the presence of glucose it was inhibited by iodoacetate, ouabain, or digoxin, but not by dinitrophenol, fluoroacetate, or anaerobiosis. The ...