A novel stability-indicating reverse phase high performance liquid chromatography method was developed and validated for the simultaneous determination of Celecoxib (CEL) and Diacerein (DIN) and its impurities in capsule dosage form. The method was developed using L1 column with gradient using the mobile phase consist of Solution A (pH = 2.3 buffer) and Solution B (methanol and acetonitrile; 50...

In nitrogen (N)-limited systems, the potential to sequester carbon depends on the balance between N inputs and losses as well as on how efficiently N is used, yet little is known about responses of these processes to changes in plant species richness, atmospheric CO2 concentration ([CO2]), and N deposition. We examined how plant species richness (1 or 16 species), elevated [CO2] (ambient or 560...

The endoplasmic reticulum stress response, also known as the unfolded protein response (UPR), has been implicated in the normal physiology of immune defense and in several disorders, including diabetes, cancer, and neurodegenerative disease. Here, we show that the apoptotic receptor CED-1 and a network of PQN/ABU proteins involved in a noncanonical UPR response are required for proper defense t...

tinere talente recrutate de profesorul Thoma Ionescu, a cărui intuiţie în alegerea colaboratorilor, viitorilor profesori de chirurgie, şefi de şcoală la rândul lor, nu a dat niciodată greş. Născut la 14 mai 1870 în oraşul Bârlad, acest fiu strălucit al pământului Moldovei, a reuşit prin calităţile sale înnăscute, dar mai ales printr-o muncă ordonată şi neobosită, să făurească o operă nepieritoa...

main purpose in this research is the explanation of different views of muslim philosophers on the p.f.c to establish an imperative religion education. reaching to this purpose we use the content analysis and logical deduction among the research methods. on the basis of the research findings, we can find two different approaches in the religious-intellectual education: popular and specialized. t...

In this study biogeochemical export in a set of catchments that vary from 6ha to almost 1500ha is investigated. Studying catchments across this large range of scales enables us to investigate the scale dependence and fundamental processes controlling catchment biogeochemical export that would not have been possible with a more limited data set. The Devil Canyon catchment, in the San Bernardino ...

Water originating from coal-bed natural gas (CBNG) production wells typically contains ammonium and is often disposed via discharge to ephemeral channels. A study conducted in the Powder River Basin, Wyoming, documented downstream changes in CBNG water composition, emphasizing nitrogen-cycling processes and the fate of ammonium. Dissolved ammonium concentrations from 19 CBNG discharge points ra...

In this paper we have analyzed the phytoestrogen content of Glycyrrhiza glabra roots harvested from four different locations in Syria. The presence of eight phytoestrogen compounds was simultaneously assessed through a LC-MS method, before and after hydrolysis. All tested extracts contain daidzein, daidzin, genistein, formononetin, ononin and coumestrol. Rezumat În această lucrare am analizat c...

1.—Composite Materials and Mechanics Laboratory, Department of Mechanical and Aerospace Engineering, New York University Tandon School of Engineering, Brooklyn, NY 11201, USA. 2.—Department of Computer Science and Engineering, New York University Tandon School of Engineering, Brooklyn, NY 11201, USA. 3.—Engineering Division, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates. 4.—Dep...

A high degree of diversity noted in the Neolithic mandibles from Abu Hureyra provided the opportunity to address the problem of the meaning and origin of variability in the population. Mandible morphology is approached bearing in mind cranio-facial interactions. Two morphological patterns were identified in the Abu Hureyra mandible sample. e ABU morph represents the majority, while the ABO mor...