A series of mono and di-N-2,3-epoxypropyl N-phenylhydrazones have been prepared on a large scale by reaction of the corresponding N-phenylhydrazones of 9-ethyl-3-carbazolecarbaldehyde, 9-ethyl-3,6-carbazoledicarbaldehyde, 4-dimethyl-amino-, 4-diethylamino-, 4-benzylethylamino-, 4-(diphenylamino)-, 4-(4,4-4'-dimethyl-diphenylamino)-, 4-(4-formyldiphenylamino)- and 4-(4-formyl-4'-methyldiphenyl-a...

In the title compound, C(18)H(19)NO, the dihedral angle between 4-methyl-phenyl and 4-(dimethyl-amino)phenyl rings is 45.5 (3)°. The C-C=C-C torsion angle of 173.8 (3)° indicates that the mol-ecule adopts an E configuration. The dimethyl-amino group is nearly coplanar with the attached benzene ring, making a dihedral angle of 2.7 (3)°. Weak inter-molecular C-H⋯π inter-actions are observed in th...

The reaction of 3,3,3-tris-(dimethyl-amino)-1-phenyl-prop-1-yne with bromine in pentane yields the title compound, C(13)H(17)N(2) (+)·Br(-). The acetyl-enic bond distance [1.197 (2) Å] is consistent with a C C triple bond. The amidinium C=N bonds [1.325 (2) and 1.330 (2) Å] have double-bond character and the positive charge is delocalized between the two dimethyl-amino groups.

The title organic-inorganic salt, (C(7)H(11)N(2))(2)[LaCl(H(2)O)(8)]Cl(4)·3H(2)O, consists of two 4-(dimethyl-amino)-pyridinium and one [La(H(2)O)(8)Cl](2+) cations, four chloride anions and three solvent water mol-ecules. In the crystal, the various units are connected by N-H⋯Cl, O-H⋯Cl, O-H⋯O and N-H⋯O hydrogen bonds, forming a network of alternating organic and inorganic layers. The 4-(dimet...

an electroorganic reaction for the synthesis of 7-amino-2, 4-dioxo-5-phenyl-2,3,4,5-tetrahydro-1h-pyrano[2, 3-d] pyrimidine-6-carbonitrile and ethyl-7-amino-2, 4-dioxo-5-phenyl-2,3,4,5-tetrahydro-1h-pyrano[2, 3-d] pyrimidine-6-carboxylate derivatives are described, using an electrogenerated base of the anion of malonitrile or ethylcyanoacetate. this one-pot, three-component condensation of an a...

Development of protocols for cryopreservation microalgae Chlorococcum dissectum Korshikov and Dunaliella salina Teodoresco requires selection effective cryoprotectants their concentrations. One the stages choosing optimal concentrations is determining degree toxicity cells at equilibration stage. Solutions dimethyl sulfoxide, ethylene glycol, ethanol, glycerol (5–30%) modified PVS1 PVS2 (50 75%...

In the reaction of 7-chloro-1,5-benzodiazepine-2,4-dione with N,N-dimethyl-formamide/dimethyl-acetal, the diazepine seven-membered ring undergoes a contraction to form the five-membered ring. The reaction yields two isomers the title compound, C(13)H(14)ClN(3)O(2); the major component has the chlorine-atom substituent in the 5-position of the benzimidazolone ring and the minor component has the...

The title compound, C(22)H(26)N(4), was prepared from p-dimethyl-amino-propiophenone in six steps. The mol-ecule has no crystallographic symmetry. The dihedral angles between the pyrazine ring and the phenyl rings are 35.81 (6) and 37.11 (8)°. The dimethyl-amino groups are essentially planar (sum of the bond angles at N = 359.3 and 359.9°) and nearly coplanar with the adjacent aromatic ring [di...

The addition of organic solvents to α-amino acids in aqueous solution could be an effective method in crystallization. We reviewed the available data on the solubility of α-amino acids in water, water-ethanol mixtures, and ethanol at 298.15 K and 0.1 MPa. The solubility of l-alanine, l-proline, l-arginine, l-cysteine, and l-lysine in water and ethanol mixtures and the solubility of l-alanine, l...