This paper presents a wideband 2 13-bit in-phase/ quadrature-phase (I/Q) RF digital-to-analog converter-based alldigital modulator realized in 65-nm CMOS. The isolation between I and Q paths is guaranteed employing 25% duty-cycle differential quadrature clocks. With a 1.3-V supply and an on-chip power combiner, the digital I/Q transmitter provides more than 21-dBm RF output power within a frequ...

Dihydropyrimidine dehydrogenase (DPD) is considered to be a key enzyme affecting the prognosis for patients with colorectal cancer. We investigated whether a correlation exists between the expression of DPD and survival in patients with colorectal cancer. The present study was designed to quantify the DPD level using an enzyme-linked immunosorbent assay in tumors and normal tissue specimens obt...

5-FU is the drug most frequently used to treat biliary tract cancer, while dihydropyrimidine dehydrogenase (DPD) is known to be a principal factor in 5-FU drug resistance. However, whether DPD activity and mRNA levels correlate with response to 5-FU is unknown for biliary tract cancers. The precise mechanism of DPD regulation also remains to be elucidated. In the present study, we quantitativel...

In this article, we propose a new robust and highly efficient digital predistortion (DPD) concept for the linearization of wideband RF power amplifiers (PAs). The proposed approach is based on combination parallelized delta-sigma modulator (DSM) forward model PA. This applies multi-rate techniques DSM that incorporates PA in its feedback loop to perform required signal predistortion. Such techn...

Recently, new emerging techniques of neuromorphic hardware render spiking neuron networks (SNN) promising as an energy-efficient solution for artificial intelligence (AI). With the idea physics informed neural network, structure can be simple while training data light. However its application in RF telecommunication system is still challenging. This paper, first time literatures, proposes a SNN...

This article presents a novel digital predistortion (DPD) approach to compensate for nonlinear dynamic distortions caused by the supply network of capacitive radio frequency digital-to-analog converters (RF-DACs). The developed DPD concept recreates voltage distortion on RF-DAC's and modulates input signal such that effects output RF-DAC are canceled. In contrast conventional approaches as prun...

  Background: Statins have been effective medications in lowering serum total cholesterol (TC) concentrations across populations over time. The aim of this study was to estimate national and provincial trends in atorvastatin sales in Iran, to systematically quantify its relationship with socio-economic indicators, and changes in TC level.   Methods : In this retrospective ecological study, cond...