Primary Hepatic Lymphoma (PHL) is rare and possibly associated with viral hepatitis and autoimmune diseases. Scleroderma could exceptionally be complicated by lymphoma. We describe PHL occurring in a 52-year-old female suffering scleroderma for eight years, with no history of cytotoxic or high-dose glucocorticoid therapy. CT scan, performed to work-up abdominal discomfort, constipation, and ...

Diffuse large B cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma worldwide, representing approximately 30-40% of all cases in different geographic regions. Patients most often present with a rapidly growing tumour mass in single or multiple, nodal or extranodal sites. The most common type of DLBCL, designated as not otherwise specified, represents 80-85% of all cases and is...

Keywords Disease name and synonyms Differential diagnosis Frequency Definition Clinical description Etiology Genetic features Diagnostic methods Staging Prognostic parameters Treatment Survival Keywords References Abstract Primary diffuse large B-cell lymphomas (DLB-CL) are aggressive tumors accounting for approximately 40% of the B-cell malignancies. DLB-CL are commonly composed of a mixture o...

Expert Panel on Radiation Oncology–Lymphoma: Bouthaina S. Dabaja, MD; Ranjana Advani, MD; David C. Hodgson, MD; Sughosh Dhakal, MD; Christopher R. Flowers, MD, MS; Chul S. Ha, MD; Bradford S. Hoppe, MD, MPH; Nancy P. Mendenhall, MD; Monika L. Metzger, MD; John P. Plastaras, MD, PhD; Kenneth B. Roberts, MD; Ronald Shapiro, MD; Sonali M. Smith, MD; Stephanie A. Terezakis, MD; Karen M. Winkfield, ...

  Background and Objective: Approximately half of patients with diffuse large B-cell lymphoma are cured with current chemotherapy regimens. The purpose of this study was to evaluate Bax and Bcl2 expression and their relationship with the response to chemotherapy. Materials and Methods This study was a prospective analysis on 44 patients with diffuse large B-cell lymphoma. Their specimens we...

Introduction: Primary gastric lymphoma (PGL) is a rare tumor, whose differential diagnosis may become complicated without precise immunohistochemistry (IHC) and genetic analysis. Case Presentation: A 33-year-old woman presented with gastric cancer and had undergone gastrectomy without precise IHC and staging in another center. Inappropriate IHC after surgery showed diffuse large B-cell lymphom...

De novo CD5+ diffuse large B-cell lymphoma (CD5+ DLBCL) is known to have phenotypically and genotypically different characteristics than CD5- DLBCL and mantle cell lymphoma (MCL). To further characterize CD5+ DLBCL, 109 patients with CD5+ DLBCL were reviewed, and the results were compared with those of 384 CD5- DLBCL and 128 cyclin D1+ MCL patients. Patients with CD5+ DLBCL showed a higher age ...

the patient was a 67-year-old female who presented with severe rectal bleeding since three days prior to hospital admission. she complained of mild abdominal pain. rectal examination revealed the presence of fresh blood and a clot. she had a normal upper endoscopy. a colonoscopy showed a large clot with bloody secretions up to the cecum, with no obvious origin. because of the severity of bleedi...

BACKGROUND CD5-positive (CD5+) diffuse large B-cell lymphoma (DLBCL) comprises ∼10% of DLBCLs, and it is associated with poor prognosis. The clinicopathologic characteristics and prognosis of CD5-negative (CD5-) DLBCL and CD5+ DLBCL were compared. PATIENTS AND METHODS The subjects were 607 DLBCL patients in whom cell surface markers could be analyzed, among 930 consecutive patients registered...

TOPIC: Lung Cancer TYPE: Medical Student/Resident Case Reports INTRODUCTION: Diffuse large B-cell lymphoma (DLBCL) may rarely manifest as a primary pulmonary or with secondary lung involvement. Typical radiologic presentations include chronic, indolent airspace consolidations, focal masses perilymphatic nodules.(1) The objective of this report is to present rare involvement DLBCL presenting bil...