Abstract Protecting science from politicization is an ongoing concern in contemporary society. Yet some political influences on (e.g., setting public funding amounts) are fully legitimate. We need to have a clear account of when influence (an illegitimate influence) order properly detect and address the problem. I argue this paper that understanding how space scientific inquiry distinctive demo...

A cosmological model with an energy transfer between dark matter (DM) and (DE) can give rise to comparable densities at the present epoch. The work deals perturbation analysis, parameter estimation Bayesian evidence calculation of interacting models dynamical coupling that determines strength interaction. We have considered two cases, where interaction is a more recent phenomenon in distant pas...

introduction: different imaging modalities are used to evaluate salivary gland diseases, including tumors. ultrasonography (us) is the preferred method on account of its ease of use, affordability, safety profile, and good tolerance among patients. the aim of this study was to evaluate the role of us in differentiating malignant from benign parotid tumors, in the context of previous controversy...

Recent studies demonstrate widespread expression of ghrelin among tissues and have uncovered its pleiotropic nature. We have examined gene expression of ghrelin and its two receptor splice variants, growth hormone secretagogue receptors (GHS-R) 1a and 1b, in human bone biopsies and in the human pre-osteoblastic SV-HFO cell line during differentiation. Additionally, we examined proliferative eff...

Cell cycle dysregulation leads to abnormal proliferation and cell death in a context-specific manner. Cell cycle progression driven via the Rb pathway forces neurons to undergo S-phase, resulting in cell death associated with the progression of neuronal degeneration. Nevertheless, some Rb- and Rb family (Rb, p107 and p130)-deficient differentiating neurons can proliferate and form tumors. Here,...

Protein kinase A (PKA) controls major aspects of neurite outgrowth and morphogenesis and plays an essential role in synaptic plasticity and memory. However, the molecular mechanism(s) of PKA action on neurite sprouting and activity are still unknown. Here, we report that in response to neurotrophin or cAMP stimulation the RING ligase praja2 ubiquitinates and degrades NOGO-A, a major inhibitor o...

detection of lymph nodes (lns) involvement by various pathological processes has great therapeutic and prognostic implications. the purpose of this study was to evaluate the usefulness and accuracy of triplex sonography (gray scale, color mapping and spectral doppler) in differentiating benign from malignant cervical lns. we used triplex sonography to evaluate 120 lns in 50 patients. the gray s...

differentiating sepsis from other noninfectious causes of systemic inflammation is often difficult in the elderly. the aim of this study was to evaluate the ability of c-reactive protein (crp), erythrocyte sedimentation rate (esr), procalcitonin (pct), and interleukin-6 (il-6) to identify elderly patients with sepsis. in this single center prospective observational study, we included all consec...

To clarify the relationship between social phobia and shyness, this study examined the characteristics of highly shy persons with social phobia, highly shy persons without social phobia, and non-shy persons. Those with social phobia reported more symptomatology, more functional impairment, and a lower quality of life than those without social phobia. About one-third of the highly shy without so...