In this work we investigated the inhibitory effect of Deltamethrin, Dichlorvos, Malathion and Lambdacyhalothrin on bovine liver catalase (CAT) activity. We observed that the inhibition of enzyme increased with increasing concentrations of the pesticides from 0 to 250 ppm. The Kinetics conformed to the MichaelisMenten model and a Lineweaver-Burk graph of CAT was drawn. To identify the inhibition...

Susceptibility of Alphitobius diaperinus (Panzer) (Coleoptera, Tenebrionidae) to cypermethrin, dichlorvos and triflumuron in southern Brazil. The lesser mealworm, Alphitobius diaperinus (Panzer), is an important insect pest in poultry houses in Brazil. Susceptibility of the lesser mealworm collected from eight poultry houses in Paraná state, southern Brazil, was evaluated for cypermethrin, dich...

Introduction Organophosphate (OP) insecticides are commonly used in veterinary practice and public health (Coggon 2002; Jaga & Dharmani 2003; Wilson 2005). They induce poisoning in mammals and avian species by irreversible inhibition of cholinesterase (ChE) activity at the nerve terminals and neuromuscular junctions causing accumulation of acetylcholine. As a result of ChE inhibition, signs of ...

OBJECTIVES The aim of the present project was to assess population exposure to pesticides in the vicinity of pesticide dump sites and make a preliminary evaluation of the potential health hazards to humans. MATERIALS AND METHODS Of the 286 pesticide dump sites registered in Poland, 40 were selected as the largest source of ecological hazard. The application of the Hazard Ranking System made i...

A liquid chromatographic-tandem mass spectrometric (LC-MS/MS) multi-residue method for the simultaneous quantification and identification of 38 residues of the most widely used anthelmintic veterinary drugs (including benzimidazoles, macrocyclic lactones, and flukicides) in milk and liver has been developed and validated. For sample preparation, we used a simple modification of the QuEChERS met...

BACKGROUND This is the first published assessment on agricultural pesticide use in Iran with the aim to identify pesticide products with a potential of causing acute or chronic hazard to human health. It also establishes a baseline for future comparisons and for trend assessments. METHODS The amounts of imported technical materials for formulation by local manufacturers as well as imported fi...

INTRODUCTION/AIM In acute organophosphate poisoning the issue of special concern is the appearance of muscle fasciculations and convulsions that cannot be adequately antagonised by the use of atropine and oxime therapy. The aim of this study was to examine atidotal effect of obidoxime or HI-6 combinations with memantine in mice poisoned with soman, dichlorvos or heptenophos. METHODS Male Albi...

cotton aphid, aphis frangulae gossypii glover, is a major pest of cucumber in iran. one of the important parasitoids playing role in population control of this pest in the fields and greenhouses is lysiphlebus fabarum marshall. in this study, we investigated sensitivity of different instars of cotton aphids and pupal stage of l. fabarum to field recommended and half-recommended concentration of...

Acylpeptide hydrolases (APHs) catalyze the removal of N-acylated amino acids from blocked peptides. Like other prolyloligopeptidase (POP) family members, APHs are believed to be important targets for drug design. To date, the binding pose of organophosphorus (OP) compounds of APH, as well as the different OP compounds binding and inducing conformational changes in two domains, namely, α/β hydro...

The inhibition kinetics of dichlorvos on carboxylesterase and acetylcholinesterase (AChE) activity extracted from Liposcelis bostrychophila and L. entomophila (Psocoptera: Liposcelididae) were compared. The results showed that L. entomophila had significantly greater specific activity of carboxylesterase than L. bostrychophila (0.045 versus 0.012 micromoles/mg/min). Moreover, the carboxylextera...