The determinants of diastolic dysfunction in patients with systemic hypertension are not completely known. To evaluate the possible role of age, arterial blood pressure, and baroreflex heart rate response impairment in causing diastolic dysfunction, we studied 61 patients (42 male; mean+/-SD age, 43.9+/-12 years) with newly recognized and therefore previously untreated systemic hypertension. Di...

The article presents the main aspects of pathogenesis comorbidity non-alcoholic fatty liver disease and hypertension. These diseases are very often presented as comorbidities in a large number patients can independently impair renal function. According to literature results our own research, role insulin resistance, disorders lipid carbohydrate metabolism, cytokine imbalance, antioxidant defens...

BACKGROUND Recent findings indicate that symptomatic heart disease in patients with diabetes mellitus predicts poor prognosis, but cardiac involvement may occur before clinical manifestation. Diastolic dysfunction may be the first stage of diabetic cardiomyopathy. OBJECTIVE The aim of this study was to evaluate the cardiovascular function in patients with DM in early stages. METHODS we stud...

BACKGROUND Previous studies in this field have not excluded right coronary artery disease by coronary angiography and have included patients with co-morbid conditions that have independent impact on right ventricular function. METHODS 14 patients with left ventricular (LV) anterior myocardial infarction (MI) due to isolated occlusion of left anterior descending coronary artery (LAD) on corona...

During the course of cirrhosis, there is a progressive deterioration of cardiac function manifested by the disappearance of the hyperdynamic circulation due to a failure in heart function with decreased cardiac output. This is due to a deterioration in inotropic and chronotropic function which takes place in parallel with a diastolic dysfunction and cardiac hypertrophy in the absence of other k...

nomic nervous system activity before surgery. Also, Jideus and colleagues concluded that ‘the diminished circadian variation in autonomic nervous system before surgery and the indirect signs of a higher parasympathetic activity in patients developing postoperative AF compared with patients remaining in sinus rhythm, may indicate a propensity for AF.’ Thus, impairment in autonomic nervous system...

INTRODUCTION  Thyroid hormone deficiency can lead to the impairment of cardiac function. OBJECTIVES  The aim of the study was to determine the left atrial (LA) mechanical function in patients with subclinical hypothyroidism (SHT) and overt hypothyroidism (OHT) and investigate associations of LA mechanical function with diastolic function.  PATIENTS AND METHODS  Twenty‑six patients with newl...

background : sensory impairment is a common condition that exerts negative effects on health-related quality of life (hrqol) in the elderly. this study aimed to determine the relationship between sensory impairment and hrqol and identify sensory-specific differences in the hrqol of elderly. methods : this study used data from the korean national health and nutrition examination survey v (2010-2...

Background Cushing’s disease (CD) has demonstrated subclinical myocardial involvement such as left ventricular (LV) hypertrophy and both diastolic and systolic impairment. Although myocardial fibrosis may play an important role in such myocardial alterations, the new T1 mapping techniques have not yet been used in CD to characterize the myocardium at baseline and to evaluate the effect of treat...

Diastolic and systolic left ventricular (LV) dysfunction often significantly contribute to disabling symptoms in familial hypertrophic cardiomyopathy (FHC). This study compares regional LV function (midwall circumferential strain) during systole and diastole in eight FHC patients and six normal volunteers (NVs) using MR tagging. A prospectively-gated fast gradient-echo sequence with an echo-tra...