BACKGROUND Foot ulceration is a major health problem for people with diabetes. To minimise the risk of ulceration, patients are advised to perform preventive foot self-care. AIM To explore beliefs about diabetic foot complications and everyday foot self-care practices among people with type 2 diabetes. DESIGN OF STUDY Qualitative study using one-to-one interviews. SETTING A suburban prima...

The main aim is Secondary Structure Prediction of proteins causing Diabetic Foot Ulcers using Artificial Neural Networks.Protein structure prediction is one of the most important goals pursued by bioinformatics. The knowledge or prediction of secondary structure improves detection and alignment of remote homologs and helps for drug design. The purpose of this study is to identify the Secondary ...

Patients: 85 patients 18–80 years of age (mean age 55 y, 51% men) who had diabetes (World Health Organization criteria) and were at high risk of developing diabetic foot ulcerations (International Working Group on the Diabetic Foot risk group 2 or 3—ie, history of foot ulceration or lower extremity amputation, or peripheral sensory neuropathy with loss of protective sensation or foot deformity ...

With the increasing prevalence of diabetes in the community, morbidity and mortality as a result of diabetic feet has been increasing. Foot complications are one of the most serious and yet preventable complications of diabetes mellitus having an economic impact to the individual and adding the burden to the already inadequate healthcare resources. Complications associated with diabetes are oft...

BACKGROUND Over the past two decades finite element (FE) analysis has become a popular tool for researchers seeking to simulate the biomechanics of the healthy and diabetic foot. The primary aims of these simulations have been to improve our understanding of the foot's complicated mechanical loading in health and disease and to inform interventions designed to prevent plantar ulceration, a majo...

DESCRIPTION A 54-year-old diabetic female patient with type 2 diabetes of 7 years’ duration presented with pain in her big toe. She had previously sustained foot ulceration several times and hence worried for recurrence. On examination she had a laminated, thickened, dark yellow toe nail of an extremely rare structure (figure1). Onychodystrophy, which is a widely used term referring to nail def...

BACKGROUND There are few studies investigating the characteristics, risk factors and socioeconomic status of patients with non-diabetic foot ulcers. The aim of this study was to explore the characteristics of non-diabetic foot ulcers in a large tertiary referral outpatient hospital setting in Western Sydney, Australia. METHODS From 2011 to 2013, data from 202 patients with non-diabetic foot u...

Diabetic foot is defined as infection, ulceration and/or destruction of deep tissues associated with neurological abnormalities and various degrees of peripheral vascular disease in the lower limb of the patients with diabetes mellitus (DM) (the International Working Group on the Diabetic Foot, 1999). Foot disorders are among the most serious and costly complications of DM (Apelqvist et al., 20...

In an attempt to define the role of autonomic neuropathy in the pathogenesis of diabetic foot ulcers, we have studied diabetic patients with and without ulcers, and a group of non-diabetic controls. A series of standard autonomic function tests have been compared with measurement of the Galvanic Skin Response (GSR). Patients with foot ulcers showed evidence of more severe somatic and autonomic ...

We investigated the relationship between serum cystatin C levels and the prognosis of diabetic foot ulcerations (DFU). A population-based cohort study involving 1018 patients with type 2 diabetes was conducted. These patients recruited and divided into two groups: nondiabetic foot ulcer group (NDF, n = 865, 85.5%) and diabetic foot ulcer group (DFU, n = 147, 14.5%).After a 1-year-follow-up, DFU...