N-methylpyrrolidone is listed under Proposition 65 (the Safe Drinking Water and Toxic Enforcement Act of 1986) as known to the state to cause reproductive toxicity (developmental toxicity), effective June 15, 2001. The Proposition 65 listing of N­ methylpyrrolidone was based on the formal identification by the U.S. Environmental Protection Agency (U.S. EPA 1994a, 1994b) of N-methylpyrrolidone a...

A workshop cosponsored by the National Institute of Environmental Health Sciences and the National Institute for Occupational Safety and Health was convened in Washington, DC, on 17-18 October 2001 with the goal of developing a consensus document on the most appropriate experimental approaches and assays available to assess developmental immunotoxicity. The work group was composed of scientists...

OBJECTIVE We reviewed studies on pulmonary, reproductive, and developmental toxicity caused by carbon nanotubes (CNTs). In paricular, we analyzed how CNT exposure affects the several processes of pulmonary toxicity, including inflammation, injury, fibrosis, and pulmonary tumors. METHODS In pulmonary toxicity, there are various processes, including inflammation, injury, fibrosis, respiratory t...

The Organisation for Economic Cooperation and Development (OECD) is an intergovernmental organisation in which representatives of 30 industrialised countries in North America, Europe and the Asia and Pacific region, as well as the European Commission, meet to coordinate and harmonise policies, discuss issues of mutual concern, and work together to respond to international problems. Most of the ...