نتایج جستجو برای: despite all
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مقاومت دارویی چندگانه (mdr) در میان محققین به عنوان مانع اصلی در درمان سرطان های مختلف به وسیله شیمی درمانی قلمداد می شود. این پدیده از طریق مکانیسم های مختلف، درنهایت موجب کاهش اثر داروهای ضدسرطان بر علیه سلول های سرطانی می گردد. یکی از بارزترین این مکانیسم ها از طریق بالا رفتن میزان بیان پروتئین های گذرنده از غشاهای سلولی اِعمال می شود که عضو ابرخانواده انتقال دهنده های متصل شونده به atp (abc)...
there are two major theories of measurement in psychometrics: classical test theory (ctt) and item-response theory (irt). despite its widespread and long use, ctt has a number of shortcomings, which make it problematic to be used for practical and theoretical purposes. irt tries to solve these shortcomings, and provide better and more dependable answers. one of the applications of irt is the as...
INTRODUCTION When I was invited as an opening speaker for this conference, I was not asked to embed it in what some call the Aarhus tradition that is now giving rise to the fourth decennial international and interdisciplinary scientific event. However, I found that I could not do otherwise. Partly, because I am full of admiration for what has been achieved, and partly because I wonder where the...
Trial ALL-BFM 90 was designed to improve outcome in patients with childhood acute lymphoblastic leukemia (ALL) by using a reduced treatment regimen. Patients were stratified into a standard-risk group (SRG), a medium-risk group (MRG), both defined by adequate early treatment response; and a high-risk group (HRG), defined by inadequate response to the cytoreductive prednisone prephase, induction...
لوسمی لنفوبلاستیک حاد ) all (acute lymphoblastic leukemia ، شایعترین بدخیمی در کودکان و نوجوانان است.ال.آسپارژیناز (l.asp) یکی از داروهایی است که در درمان بیماران مبتلا به all استفاده می شود.l.asp در سنتز پروتئین با کاتالیز واکنش تجزیه آسپارژین تداخل می کند بنابراین تولید برخی از پروتئین های انعقادی را مختل می کند و از این طریق باعث اختلال در انعقاد طبیعی می گردد. پروتئین c و پروتئین s گلیکو پر...
In this paper, we describe how to construct physical computer network topologies which can support the establishment of overlays that reduce or increase the distances between nodes. Reducing pairwise distances (i.e., compression) implies that the overlay enjoys significantly lower inter-node latencies compared to the ambient physical network; such an overlay can be used to implement a “high-per...
The phrase ‘global land grab’ has become a catch-all framework to describe and analyze the current explosion of (trans)national commercial land transactions revolving around the production and sale of food and biofuels. Initially deployed and popularised especially by activist groups deeply concerned and opposed to such transactions from an environmental-agrarian justice perspective, the signif...
BACKGROUND The aim of this study was to compare between weight and gender categories the attack and pause times during the 2007 Taekwondo World Championship. METHODS A total of 88 rounds (47 male and 41 female contests) were analyzed. RESULTS There was no difference in attack/balancing times ratio between genders (0.13 ± 0.06 vs 0.13 ± 0.06, P > 0.05). The attack number was significantly hi...
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