Human keratinocytes are able to express various antimicrobial peptides (AMP) to protect the skin from exaggerated microbial colonization and infection. Recently, in vitro growth-inhibiting activity of the skin-derived AMP psoriasin, RNase 7 and human beta-defensin (hBD)-2 against dermatophytes such as Trichophyton (T.) rubrum have been reported. To evaluate whether keratinocytes are able to res...

Dermatophytoses are superficial and contagious infections caused by dermatophyte fungi. They the most frequent infectious dermatosis in clinical practice, can affect skin, hair nails. Its correct diagnosis allows understanding of clinical, ecological epidemiological aspects associated with these microorganisms. Clinical presentation is variable depends on habitat (human, animal or soil origin),...

The symptoms of dermatophytosis goes congruent with the disease entity Padarthamarai in Siddha medicine. Kandhaga Rasayanam (KR) is a herbo-mineral formulation indicated for padarthamarai. In recent times, treatment challenge to dermatologists. present study was carried out clinically evaluate efficacy KR as trial drug Dermatophytosis. objective giving mycological and clinical cure. This an ope...

Abstract The in vitro activity of Cinnamomum cassia , Melaleuca alternifolia and Cymbopogon citratus essential oils antimycotics clotrimazole, fluconazole, ketokonazole against T. mentagrophytes was evaluated by the disc-diffusion method. were tested at 5, 10, 20, 30, 50, 100 % concentration. It found that commonly called lemongrass, cinnamon show stable results independent concentration used, ...