Dermatofibrosarcoma protuberans (DESP) is a relatively rare and low-grade tumor of the skin and soft tissue. We review the clinical features, pathological findings and management of recurrent DESP with the aim to improve our understanding of this rare tumor. Fifty-seven patients were diagnosed with recurrent DFSP. The mean age at the presentation of DFSP was 30.9 years. The mean age at diagnosi...

Background Dermatofibrosarcoma protuberans (dfsp) is a rare tumour originating from the dermis, it is slow growing, nodular, polypoid neoplasm that invade the subcutaneous tissue and does not usually metastasis.Clinical presentation is not uniform and may mimic common tropical benign skin lesions.We intend to study the behaviour of this tumour in our environment . Materails and method. A Clinic...

Dermatofibrosarcoma protuberans (DFSP) is a rare cutaneous tumor with a possibly misleading presentation. It is rare in childhood. We report an 18-month-old child with an acquired atrophic plaque of the left ankle. Based on clinical findings, initial proposed diagnoses included localized scleroderma and localized lipoatrophy. At the age of 5 years the plaque had increased in size and become a p...

Dermatofibrosarcoma protuberans is a rare cutaneous tumor with particular characteristics and a high frequency of recurrence after inadequate primary treatment. Its histopathological diagnosis might be difficult. Dermatofibrosarcoma protuberans can be safely distinguished from other similar neoplasms of mesenchymal origin based on the immunohistochemical expression of CD34 antigen and the genet...

INTRODUCTION Dermatofibrosarcoma protuberans is an uncommon low-grade soft tissue sarcoma with a high potential for recurrence as it has irregular finger like extensions. CASE DESCRIPTION We report a case of a large, recurrent dermatofibrosarcoma protuberans in a child involving the anterior abdominal wall, which posed a challenge for reconstruction. Peritoneum sparing full thickness resectio...

BACKGROUND Processing multiple tissue sections in large Mohs cases is time consuming and labor intensive. OBJECTIVE To present innovative laboratory techniques to facilitate processing of large Mohs cases. METHODS A method for processing a large dermatofibrosarcoma protuberans Mohs case is outlined. RESULTS Modifications in tissue processing and equipment employed in a large Mohs case are...

Dermatofibrosarcoma protuberans with fibrosarcomatous transformation (DFSP-FS) is a rare variant, higher rates of recurrence and metastasis than DFSP. Detection the collagen type I alpha 1 (COL1A1)–platelet-derived growth factor beta chain (PDGFB) fusion gene useful for diagnosis In this letter, we report case DFSP-FS, focusing on expression COL1A1-PDGFB in lesions. Increased may be associated ...