The effects of the androgen dihydrotestosterone (DHT) and of the androgenic steroid medroxyprogesterone acetate were studied on the growth of human ZR-75-1 breast carcinoma in athymic mice. The possibility of additive inhibitory effects of DHT and the new steroidal antiestrogen N-n-butyl, N-methyl-11-[16' alpha-chloro-3',17' alpha-dihydroxyestra-1',3',5'(10')trien-7' alpha-yl]undecanamide (EM-1...

A prospective, randomised, double-blind study of 28 patients presenting with Achilles paratendonitis was undertaken in order to evaluate the role of peritendonous injection of methy prednisolone acetate (Depo Medrone). At presentation patients were either administered peri-tendonous injection of 40 mgs of methyl prednisolone acetate suspended in 1 ml of 0.25% marcaine or 2 ml of 0.25% marcaine ...

A young girl developed extensive striae while on Depo Provera injections. She had gained some weight during the treatment. Endocrinal investigations were negative. The development of striae was attributed to her weight gain.

Medroxyprogesterone acetate (MPA) is capable of reducing male testosterone blood levels with a corresponding reduction in sexual interest and activity. An attempt to evaluate its effectiveness with court committed sexual offenders was made with eight subjects each serving as his own control by alternating Depo-Provera injections for 16 weeks with saline injections for a corresponding 16 weeks. ...

The 'ram effect' induced some seasonally anovular Southdown ewes (23%) to ovulate within 5 days of introducing Southdown rams on 10 December. Priming the ewes with medroxy progesterone acetate from intravaginal sponges for 12 days, immediately before the introduction of the rams, ensured that most of the ewes displayed oestrus at the ram-induced ovulation. The proportion of anovular ewes ovulat...

Precocious Puberty in a 2-year-old boy  A 2-year-old boy with precocious isosexual matura- (3) Lion is reported.  The pubertal values of serum LH, FSH and Testoste- (4) on and lack of any other pathologic finding were in favour of diagnosis of idiopathic sexual precocity.  The L.R.F. response test was of the adult pattern. The serum LH, FSH and Testosterone decreased following (5) treatment ...

BACKGROUND To understand the low modern contraceptive prevalence in Cameroon, we reviewed the methods chosen and determined their side effects among patients in an urban setting. METHODS We conducted a cross-sectional study at the "Cameroon National Planning Association for Family Welfare (CAMNAFAW) Clinic" in Yaoundé. Data were processed by SPSS software version 20.0 for Windows, and all tes...