Dental caries is the most common chronic childhood disease. Deep caries and dental trauma are the two main etiologic factors responsible for pulp involvement. Better knowledge of the morphology of the root canals of deciduous teeth can improve the outcome of pulp treatment. In this study, 90 deciduous molar teeth (27 first mandibular molars, 27 first maxillary molars, 22 second mandibular molar...

objective: various techniques of composite placement have been used to decrease microleakage around the composite restorations. due to controversial results, the present study was conducted to investigate the effect of different placement techniques on microleakage in class v composite restorations. materials and methods: sixty class v cavities were prepared on the buccal and lingual surfaces o...

diabetes mellitus is a chronic disease which affects the healing ability of the pulp and periodontium. the aim of the present study was to assess the histopathologic response of dental pulp to pulp capping using mta or cem cement in diabetic rats. thirty two wistar male rats aged between 8 and 10 weeks (weight: 200-250g) were divided into two groups of diabetic (n=16) and healthy (n=16) animals...

BACKGROUND Precise assessment of dental pulp anatomy is of an extreme importance for a successful endodontic treatment. As standard radiographs of teeth provide very limited information on dental pulp anatomy, more capable methods are highly appreciated. One of these is 3D magnetic resonance (MR) microscopy of which diagnostic capabilities in terms of a better dental pulp anatomy assessment wer...

The regenerative potential of dental pulp is very limited in mature teeth. However, our improved understanding of pulpal inflammation and repair and improved dental materials and technologies make vital pulp therapy a viable alternative to root canal treatment. This article explores our knowledge in this regard and the future potential of saving or even regenerating the pulp as a routine dental

BACKGROUND AND OBJECTIVE Dental pulp repair is a common process triggered by microbial and mechanical challenges. Matricellular modulators, such as periostin, are key for extracellular matrix stability and tissue healing. In the scope of the dental pulp, periostin expression has been reported during development and active dentinogenesis. However, the specific dental pulp cell population capable...

Dental Caries affects approximately 90% of the world's population. At present, the clinical treatment for dental caries is root canal therapy. This treatment results in loss of tooth sensitivity and vitality. Tissue engineering can potentially solve this problem by enabling regeneration of a functional pulp tissue. Dental pulp stem cells (DPSCs) have been shown to be an excellent source for pul...

stem cell-based therapy has great potential in treating health conditions including cardiovascular, autoimmune, type i diabetes, neurodegenerative and bone and cartilage diseases also in spinal cord injuries, malformations and cancer. in addition to their potential use to treat systemic diseases, stem cell-based therapy also provides a powerful tool to treat oral and dental diseases such as cra...

Innate immunity represents the first line of defence against infectious agents and is essential for the detection of pathogens invading the host. Unless adaptive immunity, innate immunity is considered as non-specific as it is antigen-independent and reacts similarly to a variety of micro-organisms. It is responsible for mounting potent inflammatory responses that bring to infected tissues a va...