Introduction Quantification of carious lesions and measurement of the distance to the pulp is an important task in conservative dentistry. This information can improve identification of cases with the potential for maintaining pulp vitality and monitor treatment success of indirect pulp capping. In the procedure of indirect pulp capping the nearly exposed pulp is covered with a chemical (usuall...

Inflammatory response in the dental pulp can alter the collagen matrix formation by dental pulp stem cells and lead to a delay or poor healing of the pulp. This inflammatory response is mediated by cytokines, including interleukin-1β and tumor necrosis factor-α. In this study, it is hypothesized that suppressing the actions of these inflammatory cytokines by knocking down the activity of transc...

In 6 dogs, experiments were performed to determine the tissue reaction of the dental pulp at the 7, 30 and 60 days after direct contact of the pulp with the obturation material through a microcommunication orifice with diameter up to 1 mm, formed in the fundic part of an experimental cavity. Capping of 36 mandibular premolars with traumatically exposed pulp was carried out. On the exposed pulp,...

Dental caries is one of the most widely prevalent infectious diseases in the world. It affects more than half of the world's population. The current treatment for necrotic dental pulp tissue arising from dental caries is root canal therapy. This treatment results in loss of tooth sensitivity and vitality making it prone for secondary infections. Over the past decade, several tissue-engineering ...

Dental pulp stem/progenitor cells guarantee tooth homeostasis, repair and regeneration throughout life. The decision between renewal and differentiation of these cells is influenced by physical and molecular interactions with stromal cells and extracellular matrix molecules forming the specialized microenvironment of dental pulp stem cell niches. Here we study the activation of putative pulp ni...

Human deciduous and permanent teeth exhibit different developmental processes, morphologies, histological characteristics and life cycles. In addition, their pulp tissues react differently to external stimuli, such as the pulp sensitivity test, dental trauma and pulp therapy materials. These suggest differences in gene expression and regulation, and in this study we compared gene-expression pro...

Considering the ease of isolation and high expansion potential of pulp stem/progenitor cells isolated from wisdom and primary teeth they have been implicated as the most reliable autologous cell source in dental tissue engineering. Meanwhile, different isolation methods have remarkable impacts on the expansion potential of adult stem cells. In enzymatic digestion method extracted teeth as denta...

this article describes successful use of calcium-enriched mixture (cem) cement and biodentine in apexogenesis treatment in two 8-year-old patients, one with immature permanent molar diagnosed primarily with irreversible pulpitis and the other with partially vital maxillary central incisor. after access cavity preparation, partial pulpotomy in molar and full pulpotomy in central was performed, a...

this case report presents endodontic management of a mandibular lateral incisor with three canals using surgical dental operating microscope. this study describes the root canal variation of mandibular lateral incisor and highlights the importance of surgical operating microscope in detecting an unusual canal morphology.

www.endojournal.com.ar 540 Dental pulp is a highly vascularized and innervated tissue. The neural component of the pulp tissue consists of motor and sensory nerve fibers, the latter coming from the cranial nerve V; all stimuli that provoke these fibers will result in a painful sensation. Dental pulp tissue is not the only tissue with this characteristic. The eye cornea and the tympanic membrane...