Introducción El vítreo ocupa el espacio comprendido entre el cristalino y la retina. Su función es dar soporte a las estructuras oculares manteniendo la presión intraocular y permitiendo el paso de la luz hasta la retina; además, brinda la nutrición del cristalino y la retina (1). Su desarrollo embriológico es bastante complejo y se origina a partir del mesénquima dentro de la copa óptica duran...

VISTO lo Statuto dell'Università degli Studi di Catania; VISTA la Legge 30.12.2010, n° 240, recante "norme in materia di organizzazione delle università, di personale accademico e reclutamento, nonché delega del Governo per incentivare la qualità e l'efficienza del sistema universitario", ed in particolare l'art. 18, co.5, lett. fi VISTA la legge 04.04.2012, n° 35 di "Conversione in legge, con ...

Developmental endothelial locus-1 (Del-1) is an endothelium-derived anti-inflammatory molecule that is downregulated by inflammatory stimuli. Little is known about the molecular mechanisms by which Del-1 transcription is regulated. In the present study, a DNA sequence upstream of the Del-1 gene was analyzed and putative p53 response elements (p53REs) were identified. An approximately 2 kb fragm...

The development of the so-called Web 2.0 introduces a number of applications that have led to new ways and communication channels. The advance in these technologies has originated an increased interest in the development of virtual worlds during the last decade. In this paper we present a specific use of natural language proccesing and speech tecnologies in these environments through the integr...

Developmental endothelial locus-1 (Del-1) is an endothelial cell-secreted protein that limits the recruitment of neutrophils by antagonizing the interaction between the LFA-1 integrin on neutrophils and the intercellular adhesion molecule (ICAM)-1 on endothelial cells. Mice with genetic or age-associated Del-1 deficiency exhibit increased neutrophil infiltration in the periodontium resulting in...

Elisa Morgera. Editor de Contenido Digital: Anders Gonçalves da Silva. Traducción al español: Socorro Estrada. Editora: Pamela S. Chasek, Ph.D. . Director de Servicios Informativos del IIDS: Langston James “Kimo” Goree VI . Los donantes permanentes del Boletín son el Gobierno de los Estados Unidos (a través del Bureau de Océanos y Asuntos Ambientales y Científicos I...

RESUMEN La finalidad del trabajo fue evaluar la percepción del paciente portador de un Catéter Totalmente Implantado (CTI). Se trata de un estudio descriptivo, que utiliza para el análisis de los datos la Técnica de los Incidentes Críticos (IC). Fue desarrollado en un Hospital Escuela del interior de Sao Paulo-Brasil, del cual participaron 15 porta-dores de CTI. Los datos fueron agrupados en 4 ...

Del-1 is an endothelial cell-secreted anti-inflammatory protein. In humans and mice, Del-1 expression is inversely related to that of IL-17, which inhibits Del-1 through hitherto unidentified mechanism(s). Here we show that IL-17 downregulates human endothelial cell expression of Del-1 by targeting a critical transcription factor, C/EBPβ. Specifically, IL-17 causes GSK-3β-dependent phosphorylat...

La analogía del síndrome metabólico de la obesidad común (idiopática) con el síndrome de Cushing, ha suscitado la hipótesis de que cierto grado de hipercortisolismo subyacería a la concurrencia de alteraciones metabólicas e hipertensión arterial del síndrome metabólico1. En efecto, una serie de parámetros indicadores del metabolismo del cortisol se correlacionan positivamente con componentes de...

We enrolled 151 healthy mother/newborn couples and 26 with gestational diabetes mellitus (GDM). HLA-G and PAPP-A plasma levels were measured by ELISA at first and second trimesters, at delivery, and in cord blood. HLA-G 14 bp ins/del and PAPP-A A/C polymorphisms were genotyped. HLA-G del/del and PAPP-A C/C genotypes were more frequent among GDM mothers than controls. We observed a genetic epist...