نتایج جستجو برای: degradable protein

تعداد نتایج: 1237092  

2017
Kyle J. Vander Pol Galen E. Erickson Terry J. Klopfenstein

Fifty-eight crossbred yearling heifers (BW = 383 ± 25 kg) were utilized in a completely randomized 2 x 2 factorial arrangement of treatments designed to evaluate the effects of finishing diets containing dried distiller's grains supplemented with degradable intake protein on feedlot performance and carcass characteristics. Dietary treatments contained 10 or 20% dried distiller's grains (DDG) re...

2014
Kathryn A. Whitehead J. Robert Dorkin Arturo J. Vegas Philip H. Chang Omid Veiseh Jonathan Matthews Owen S. Fenton Yunlong Zhang Karsten T. Olejnik Volkan Yesilyurt Delai Chen Scott Barros Boris Klebanov Tatiana Novobrantseva Robert Langer Daniel G. Anderson

One of the most significant challenges in the development of clinically viable delivery systems for RNA interference therapeutics is to understand how molecular structures influence delivery efficacy. Here, we have synthesized 1,400 degradable lipidoids and evaluate their transfection ability and structure-function activity. We show that lipidoid nanoparticles mediate potent gene knockdown in h...

2017
Guang Liu Zhiwei Fang Minglu Yuan Weimin Li Yunqi Yang Mier Jiang Yuanming Ouyang Weien Yuan

The safe and efficient delivery of therapeutic nucleic acid is a prerequisite for an effective DNA therapy. In this study, we condensed the low molecular weight polyethylenimine (PEI, 1.8k Da) with 2,6-pyridinedicarboxaldehyde (PDA), both of which are degradable in vivo, to synthesize a biodegradable polycationic material (PDAPEI) to deliver vascular endothelial growth factor (VEGF) plasmid DNA...

2003
X. Huang B. R. Nayak

A series of multi-functional hydrogel systems have been designed and synthesized for potential brain implantation to realize controlled and sustained release of Nerve Growth Factor (NGF) for the treatment of Alzheimer’s disease (AD). The systems are three-dimensional crosslinked copolymers composed of a thermo-responsive unit, a hydrolytically degradable and hydrophobic unit, and an enzymatical...

Journal: :Journal of materials chemistry. B 2014
Prathamesh M Kharkar April M Kloxin Kristi L Kiick

Journal: :IEEE Trans. Information Theory 2014
Ciara Morgan Andreas J. Winter

We exhibit a possible road towards a strong converse for the quantum capacity of degradable channels. In particular, we show that all degradable channels obey what we call a “pretty strong” converse: When the code rate increases above the quantum capacity, the fidelity makes a discontinuous jump from 1 to at most 1 √ 2 , asymptotically. A similar result can be shown for the private (classical) ...

2005
O. Canbolat A. Kamalak E. Efe M. Sahin C. O. Ozkan

The objective of this study was to determine the effect of the heat treatment of full-fat soyabean (FFSB) and solvent extracted soyabean meal (SBM) on the in situ dry matter (DM) and protein degradability, and in vitro gas production kinetics of the protein sources. Ruminal disappearance of DM and crude protein (CP), and in vitro gas production were determined after 0, 4, 8, 16, 24, 48 and 72 h...

2013
Prathamesh M. Kharkar Kristi L. Kiick April M. Kloxin

Degradable and cell-compatible hydrogels can be designed to mimic the physical and biochemical characteristics of native extracellular matrices and provide tunability of degradation rates and related properties under physiological conditions. Hence, such hydrogels are finding widespread application in many bioengineering fields, including controlled bioactive molecule delivery, cell encapsulati...

2006
P. Chanjula M. Wanapat C. Wachirapakorn

Eight crossbred (75% Holstein Friesian) cows in mid-lactation were randomly assigned to a switchback design with a 2x2 factorial arrangement to evaluate two nonstructural carbohydrate (NSC) sources (corn meal and cassava chips) with different rumen degradability and used at two levels of NSC (55 vs. 75%) with protein source (supplied by urea in the concentrate mix). The treatments were 1) Low d...

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