نتایج جستجو برای: deep brain stimulation
تعداد نتایج: 886866 فیلتر نتایج به سال:
BACKGROUND Positive clinical outcomes are now well established for deep brain stimulation, but little is known about the effects of long-term deep brain stimulation on brain structural and functional connectivity. Here, we used the rare opportunity to acquire pre- and postoperative diffusion tensor imaging in a patient undergoing deep brain stimulation in bilateral subthalamic nuclei for Parkin...
Deep brain stimulation (DBS) is known as the most effective technique in the treatment of neurodegenerative diseases, especially Parkinson disease (PD) and epilepsy. Relative healing and effective control of disease symptoms are the most significant reasons for the tangible tendency in use and development of this technology. Nevertheless, more cellular and molecular investigations are required ...
It is established that deep brain stimulation of the subthalamic nucleus improves motor function in advanced Parkinson's disease, but its effects on autonomic function remain to be elucidated. The present study was undertaken to investigate the effects of subthalamic deep brain stimulation on gastric emptying. A total of 16 patients with Parkinson's disease who underwent bilateral subthalamic d...
Deep brain stimulation therapy is an effective symptomatic treatment for Parkinson's disease, yet the precise mechanisms responsible for its therapeutic effects remain unclear. Although the targets of deep brain stimulation are grey matter structures, axonal modulation is known to play an important role in deep brain stimulation's therapeutic mechanism. Several white matter structures in proxim...
This critical review examines the effects of two different types of neurosurgical interventions for generalized dystonia, brain lesioning procedures and deep brain stimulation (DBS). Study designs include: single-group posttest only (2), single-group pre-posttest (3), and mixed (between and within) randomized clinical trial (1). Reports on brain lesioning studies showed evidence that surgery ha...
abstract introduction: it is demonstrated that the degree of clinical improvement in parkinson's disease (pd) achieved by deep brain stimulation (dbs) is largely dependent on the accuracy of lead placement. in addition, individual variability in the situation of subthalamic nucleus (stn) is responsible for spatial inter-individual fluctuations of the real patient's target. objective: our study ...
Ahmad Alhourani, Michael M. McDowell, Michael J. Randazzo, Thomas A. Wozny, Efstathios D. Kondylis, Witold J. Lipski, Sarah Beck, Jordan F. Karp, Avniel S. Ghuman, and R. Mark Richardson Department of Neurosurgery, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania; and Center for the Neural Basis of Cognition, Pittsb...
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