نتایج جستجو برای: daz gene
تعداد نتایج: 1141522 فیلتر نتایج به سال:
Sustained monoculture often leads to a decline in soil quality, in particular to the build-up of pathogen populations, a problem that is conventionally addressed by the use of either fungicide and/or soil fumigation. This practice is no longer considered to be either environmentally sustainable or safe. While the application of organic fertilizer is seen as a means of combating declining soil f...
خانواده ژنی daz ، گروهی از پروتئین های متصل شونده به rna را کد می نمایند که بیان آنها در سلول های جنسی در دوران قبل و بعد از تولد می باشد. به همین سبب اعضای این خانواده ژنی، کاندید مهمی برای ناباروری در مردان محسوب می شوند .این خانواده دارای سه عضو، دو ژن اتوزومال boule/dazl و یک خوشه ژنی موجود در کروموزوم y به نام daz میباشد. موتاسیون یا پلی مورفیسم در ژن daz می تواند منجر به ناباروری در مردان...
BACKGROUND We have previously demonstrated that the Y-specific ampliconic fertility genes DAZ (deleted in azoospermia) and CDY (chromodomain protein Y) varied with respect to copy number and position among chimpanzees (Pan troglodytes). In comparison, seven Y-chromosomal lineages of the bonobo (Pan paniscus), the chimpanzee's closest living relative, showed no variation. We extend our earlier c...
Y chromosome microdeletions are the most frequent genetic cause of severe oligozoospermia (,5 million spermatozoa/ml) and azoospermia (absence of spermatozoa in the ejaculate). Microdeletions associated with infertility occur in specific regions of the long arm of the Y chromosome, called azoospermia factor (AZF) regions. 3 In 1996, three types of AZF deletion (AZFa, AZFb, and AZFc) were descri...
INTRODUCTION Although assisted reproduction techniques are used extensively in Iran, screening for Y chromosome microdeletions before intracytoplasmic sperm injection is often undervalued. Our aim was to investigate Y chromosome microdeletions in men with idiopathic azoospermia or severe oligospermia. MATERIALS AND METHODS In 99 selected patients with azoospermia or severe oligospermia and el...
STUDY QUESTION What are the genetic causes for the predisposition of certain Y chromosome haplogroups (Y-hgs) to spermatogenic impairment? SUMMARY ANSWER The AZFc(azoospermia factor c)/DAZ (deleted in azoospermia) duplications might underlie the susceptibility of Y-hg K* to spermatogenic impairment. WHAT IS KNOWN ALREADY The roles of Y chromosomal genetic background in spermatogenesis are c...
Y chromosome microdeletions are the most frequent genetic cause of severe oligozoospermia (,5 million spermatozoa/ml) and azoospermia (absence of spermatozoa in the ejaculate). Microdeletions associated with infertility occur in specific regions of the long arm of the Y chromosome, called azoospermia factor (AZF) regions. 3 In 1996, three types of AZF deletion (AZFa, AZFb, and AZFc) were descri...
We present near-infrared spectroscopic observations of 20 previously known DAZ white dwarfs obtained at the NASA Infrared Telescope Facility. Two of these white dwarfs (G29-38 and GD 362) are known to display significant K-band excesses due to circumstellar debris disks. Here we report the discovery of excess K-band radiation from another DAZ white dwarf, WD 0408 041 (GD 56). Using spectroscopi...
AIM To explore the possible effect of the deleted in azoospermia (DAZ) copy cluster deletion on spermatogenesis in the Chinese population, the deletion of the azoospermia factor c (AZFc) region was analyzed in 346 normozoospermic men. METHODS Three DAZ single nucleotide variant loci and seven AZFc-specific sequence-tagged sites were examined with polymerase chain reaction (PCR)-restriction fr...
Gametogenesis is a complex process subject to strict controls at both levels of transcription and translation. Members of a family of conserved RNA-binding proteins encoded by the DAZ genes are required for the translational regulation of gene expression essential for this process. Although loss of DAZ family genes is associated with infertility in several organisms including humans, the identi...
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