نتایج جستجو برای: das28
تعداد نتایج: 1719 فیلتر نتایج به سال:
To cite: Tanaka Y, Hirata S, Kubo S, et al. Ann Rheum Dis Published Online First: [please include Day Month Year] doi:10.1136/ annrheumdis-2013-204016 ABSTRACT Objectives To investigate the possibility of discontinuing adalimumab (ADA) for 1 year without flaring (DAS28erythrocyte sedimentation rate (ESR) ≥3.2), and to identify factors enabling established patients with rheumatoid arthritis (RA)...
©2018 Turkish League Against Rheumatism. All rights reserved. ABSTRACT Objectives: This study aims to evaluate the effects of passive smoking on disease activity in female patients with rheumatoid arthritis (RA). Patients and methods: Among a total of 191 female patients with RA (mean age 59.1±12.5 years; range 21 to 87 years) consecutively recruited, 100 female patients (mean age 56.1±13.4 yea...
INTRODUCTION Rheumatoid arthritis (RA), a chronic inflammatory disease, is associated with insulin resistance. Experimental evidence indicates that the relationship between insulin resistance and inflammation is bidirectional: Inflammation promotes insulin resistance, and insulin resistance promotes inflammation. Therefore, we examined the hypothesis that pioglitazone, a thiazolidinedione perox...
The Disease Activity Score using 28 joint counts (DAS28) has been developed in a cohort of patients with rheumatoid arthritis in which only conventional anti-rheumatic treatments were used. It has extensively been validated to monitor disease activity in daily clinical practice as well as in clinical trials. The study of Vander Cruyssen and colleagues showed that the DAS28 correlated best with ...
OBJECTIVE To investigate how antibodies against anti-tumour necrosis factor (anti-TNF) agents influence response after switching from infliximab to adalimumab in rheumatoid arthritis (RA). METHODS This cohort study consisted of 235 patients with RA, all treated with adalimumab. At baseline 52 patients (22%) had been previously treated with infliximab ('switchers'), and 183 (78%) were anti-TNF...
مقدمه: برخی مطالعات اندازه گیری تیتر anti-mcv (anti-mutated citrullinated vimentin antibodies) را به عنوان یک تست اختصاصی برای تشخیص و پیشرفت بیماری آرتریت روماتویید شناخته و سطح آن را با نمره ی فعالیت بیماری ( disease activity score calculator for rheumatoid arthritis یا das28) مرتبط دانسته اند. هدف ما از انجام این مطالعه، بررسی ارتباط تیتر این آنتی بادی با فعالیت بیماری و تغییرات آن طی درمان ...
background: rheumatoid arthritis (ra) is a chronic, systemic, inflammatory disease with autoimmune etiology, characterized by synovial inflammation and destruction of joint cartilage and bone. there are controversial data about the profile of interleukin-17 (il-17a), interleukin-4 (il-4), and interferon-gamma (infî³), indicating in some studies the key role of il-17, while in others the th1 cyt...
A considerable proportion of children with polyarticular juven-ile idiopathic arthritis (polyJIA) experience active disease into adulthood. However, there is no validated disease activity measure for adults with polyJIA, and they are often assessed using the disease activity score 28 (DAS28). DAS28 is validated in adults with rheumatoid arthritis (RA), and determines qualification for biologica...
OBJECTIVE When one TNFalpha blocker (etanercept or infliximab) has failed, to determine whether it makes sense to treat patients with the other. PATIENTS AND METHODS Since 1999 patients treated with etanercept or infliximab have been systematically followed up at our institution in the STURE database. We identified 31 patients who had received both agents. RESULTS Eighteen patients received...
We report three cases of previous smokers who did not respond to TNF inhibitors but who responded successfully to an anti-interleukin-6 receptor antibody (tocilizumab (TCZ)). Case 1 is a 63-year-old woman whose smoking index was 200 and had been complaining of polyarthralgia since 1996. She started treatment with etanercept due to high disease activity, but her DAS28-CRP was 4.2. She was theref...
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