One of the disadvantages of using OFDM is the larger peak to averaged power ratio (PAPR) of the time domain signal as compared with the conventional single carrier transmission method. The OFDM signal with larger PAPR will cause the undesirable spectrum regrowth and the larger degradation of bit error rate (BER) performance both due to the inter-modulation products occurring in the non-linear a...

In Escherichia coli, the replication origin oriC consists of two functional regions: the duplex unwinding element (DUE) and its flanking DnaA-assembly region (DAR). ATP-DnaA molecules multimerize on DAR, unwinding DUE for DnaB helicase loading. However, DUE-unwinding mechanisms and functional structures in DnaA-oriC complexes supporting those remain unclear. Here, using various in vitro reconst...

Considering the fact that many Muslims with diabetes prefer to fast in spite of inhibitory advises and to answer several conflicts and controversies regarding diabetes and Ramadan, IDF in collaboration with Diabetes and Ramadan (DAR) International in Alliance decided to develop a comprehensive guideline to be used by health care professionals. This guideline was then developed on April 2016 by ...

In our previous analysis of nucleon-nucleon (NN) elastic scattering data [1], the upper energy limit was extended from 2.5 to 3.0 GeV in the laboratory kinetic energy, Tp, in order to accomodate higher-energy proton-proton (pp) scattering measurements from SATURNE II at Saclay and the EDDA Collaboration at COSY. Comparisons were made with the direct amplitude reconstruction (DAR) and partial-wa...

Ein wichtiger Baustein des neu entdeckten World Wide Web – des ”Web 2.0“ – stellen Folksonomies dar. In diesen Systemen können Benutzer gemeinsam Ressourcen verwalten und mit Schlagwörtern versehen. Die dadurch entstehenden begrifflichen Strukturen stellen ein interessantes Forschungsfeld dar. Dieser Artikel untersucht Ansätze und Wege zur Entdeckung und Strukturierung von Nutzergruppen (”Commu...

Implementasi Kitab Nubdzatul bayan dalam pembelajaran Nahwu dan shorrof bagi pemula di Ma’had Aly Nurul Jadid dengan menggunakan berbagai metode untuk memudahkan cara belajar mahasantri, Penelitian ini bertujuan mengatahui efektifitas implementasi kitab terhadap nahwu yang mana seorang guru harus mampu mengimplementasikan Nudzatul Bayan pendalaman qowaid (nahwu shorrof), kedua ilmu tersebut ber...

Previous work has demonstrated that in utero cocaine exposure induces an uncoupling of brain D(1A) dopamine receptors (D(1A)DARs) from G(s)-protein. The present work is an attempt to define the mechanism underlying the uncoupling. We detected a significant elevation of phosphoserine in frontal cortical D(1A)DARs of rabbits that were exposed prenatally to cocaine compared with saline controls. T...

INTRODUCTION Dopamine (DA) binds to five receptors (DAR), classified by their ability to increase (D1R-like) or decrease (D2R-like) cAMP. In humans, most DA circulates as dopamine sulfate (DA-S), which can be de-conjugated to bioactive DA by arylsulfatase A (ARSA). The objective was to examine expression of DAR and ARSA in human adipose tissue and determine whether DA regulates prolactin (PRL) ...

ADC bioanalytical strategies With the US FDA approval of Adcetris® (brentuximab vedotin) in 2011 and Kadcyla® (ado-transtuzumab emtansine) in 2013, antibody-drug conjugate (ADC) has been a hot topic in industry. Because of the complexity of an ADC, combining monoclonal antibody and small molecule toxin, its bioanalysis has seen unprecedented amount of discussion compared to other drug modalitie...