Cdc14 in good repair C dc14 is an essential regulator of the yeast cell cycle, but its vertebrate homologues appear to be surprisingly dispensable, Mocciaro et al. report. They are required for effi cient DNA repair, however. Yeast Cdc14 is a phosphatase that counteracts the cyclin-dependent kinases to control many aspects of the cell cycle including mitotic exit. Vertebrates have at least two ...