BACKGROUND Sickle cell disease (SCD) has extremely variable phenotypes, and several factors have been associated with the severity of the disease. OBJECTIVES To analyze the chronic complications of SCD and look for predictive risk factors for increased severity and number of complications. METHODS Retrospective study including all children followed for SCD in the Paediatric Haematology Unit...

1 of 3 DESCRIPTION We describe the case of a 75-year-old man with a history of chronic lymphoid leukaemia stage B in Binet system treated by chemotherapy with chlorambucil and prednisolone. The patient was in complete remission with this treatment for 3 years. When he presented to our department, he complained of two painful and indurated swellings in the right fi fth fi nger and in the right w...

Objectives: To further characterise spontaneous arthritis in aging male DBA/1 mice as a model of spondyloarthropathy and psoriatic arthritis with particular attention to signs of inflammation and nail involvement. Materials and methods: Aging male DBA/1 mice from different litters were caged together (4–6 mice per cage) at the age of 12 weeks, checked twice a week for signs of arthritis, and ki...

Twenty-six patients with a pauciarticular arthritis have been studied clinically, radiologically and with histocompatibility typing. An increased frequency of HLA B27 was found (p = 1.87 x 10(-12)). Low back and buttock pain, Achilles tendinitis and dactylitis of the toes were more frequent in HLA-B27 positive patients. It is suggested that histocompatibility testing may be of some value in dia...

Introduction: Skeletal tuberculosis of the small tubular bones of hand and feet is less frequently encountered. It accounts for less than 1% of extra pulmonary tuberculosis with spine being the most frequent site of involvement. Small bones of hand area involved with greater frequency than the foot and condition is relatively rarer after the age of 5 years. Fine needle aspiration cytology is an...

Cases of tuberculosis with multisystemic involvement are rarely reported and these are often children and patients with AIDS whose and immune system is suppressed. Tuberculosis can mimic and present with various disorders. A 18-year-old Georgian male patient was admitted to the hospital with double vision, swelling and wound on the 3rd digit of the right hand. We defined the multisystemic tuber...