Mixture experiments are usually designed to study the effects on response by changing relative proportions of mixture ingredients. This is achieved keeping total amount fixed but in many practical applications such as medicine or biology, not only ingredients involved also their particular interest. Such called experiments. In experiments, usual constraint that they should sum unity relaxed. Th...

the binary and ternary codes spanned by the rows of the point by block incidence matrices of some 2-designs and their complementary and orthogonal designs are studied. a new method is also introduced to study optimal codes.

the present study was undertaken to develop a suitable transdermal matrix patch of ketorolac tromethamine with different proportions of polyvinyl pyrrolidone (pvp) and ethyl cellulose (ec) using a d-optimal mixture design. the prepared transdermal patches were subjected to different physicochemical evaluation. the surface topography of the patches was examined by scanning electron microscopy (s...

In this paper, the composition of binary nonazeotropic working fluids is explored from perspective improving OTEC-ORC efficiency, and turbine designed to accommodate with fluid. It found that using a R152a/R32 mixture as fluid significantly higher than thermal efficiency system pure NH3, optimal mixed determined be 85 : 15 2.8% 1.7%, respectively, by 35.7% 151.2% compared NH3 ORC. According flu...

The objective of the present study was to design and develop a microemulsion based transungual drug delivery formulation of ciclopirox olamine using colloidal carrier for treatment of onychomycosis. Capmul PG8 was selected as oil phase due to the high solubility of ciclopirox in it as compared to other oils and Cremophor EL and Transcutol P were used as surfactant and cosurfactant respectively....