characterization of isolated pigeon paramyxovirus-1 (pmv-1) and its pathogenicity in broiler chickens were studied. two hundred and thirty-two samples collected from 50 unvaccinated pigeons lofts suspected to newcastle disease from private houses and bird markets from ahvaz , iran. swab samples from cloaca and oropharynx of live pigeons and from trachea, lung, liver, spleen, kidney, brain, prov...

colon cancer is cancer of the large intestine (colon), the lower part of digestive system and the third most common cancer in men and the second most common cancer in women worldwide. genetic background is thought to play a role in modulating individual risk to this cancer. many studies support an association for insulin pathway gene polymorphisms and   the regulation of tumor cell biology in c...

in a r etrospective s t udy on the c ancer o f the gal l bladder, done in iran, it s e ems tha t it compr ises 0 . 36% o f a ll the malignant tumors . 1 .7 5% of the patients were fema les and the maximum incidenc e wa s in t he s i x th decade of l i f e. it was interesting t o note that the age ratio bet ween t he males and f ema le s reverses with t he advance o f a ge, s o at the 7th and 8t...

purpose : the objective of this study was to investigate the total antioxidant status (tas) and dna damage markers of serum and aqueous humor in patients with pseudoexfoliation (pex) syndrome. methods : twenty-seven cataract patients with pex and twenty-seven without pex syndrome were included in the study and groups were matched for age and gender. patients had no elevated intraocular pressure...

new derivatives of 2-[2-(2-chlorophenoxy)phenyl]-1,3,4-oxadiazole as candidates for agonistic effect on benzodiazepine receptors were synthesized. conformational analysis and superimposition of energy minima conformers of the novel compounds on estazolam, a known benzodiazepine agonist, revealed that the main proposed benzodiazepine pharmacophores were well matched. in pharmacological evaluatio...

chiral pyrrolidines and pyrrolizidines with spirooxindole ring systems are the central skeletons for numerous alkaloids and pharmacologically important compounds. gelesmine, pseudotabersonine, formosanine, isoformosanine, morroniside and mitraphylline are some of the alkaloids containing spirooxindole ring systems. derivatives of spirooxindole find very wide biological applications as anti micr...

background: interleukin (il)-8 plays important roles in the recruitment and activation of immune cells during visceral leishmaniasis (vl). genetic variations in il-8 modulate the expression of il-8 protein and may be associated with vl. this study aimed to evaluate polymorphisms at the il-8 −251 position in vl patients. methods: this cross-sectional study was performed on three groups: leishman...

a general synthetic route for the synthesis of 1,2-dihydro-1-aryl-naphtho[1,2-e][1,3]oxazine-3-one derivatives has been developed using perlite-so3h nanoparticles as efficient catalyst under both microwave-assisted and thermal solvent-free conditions. the combination of 2-naphthol, aldehyde and urea enabled the synthesis of 1,2-dihydro-1-aryl-naphtho[1,2-e][1,3]oxazine-3-one derivatives in the ...

objective(s) 7-prenyloxycoumarins including 7-isopentenyloxycoumarin, auraptene and umbelliprenin, and herniarin have been widely recognized as bioactive coumarins. this paper presents the ways to synthesis these compounds. materials and methods 7-prenyloxycoumarins were synthesized by reaction between 7-hydroxycoumarin (' m) and relevant prenyl bromides (1.5 m) in acetone at room temperat...