The value of nursing care coordination: A white paper of the American Nurses Association Michelle Camicia, MSN, RN, CRRN, Barbara Chamberlain, PhD, MBA, APRN, CCRN, Rhonda Ray Finnie, BSN, RN, CNOR, RNFA, Maureen Nalle, PhD, RN, Linda L. Lindeke, PhD, RN, Lourdes Lorenz, RN, MSN-IH, NEA-BC, AHN-BC, Debra Hain, DNS, APRN, GNP-BC, Kenya D. Haney, BSN, RN, Nancy Campbell-Heider, PhD, FNP, NP-C, CA...

In this study, a glycyrrhetinic acid-functionalized mesoporous silica nanoparticle (MSN-GA) was prepared for active tumor targeting. MSN-GA exhibited satisfactory loading capacity for insoluble drugs, uniform size distribution, and specific tumor cell targeting. Glycyrrhetinic acid, a hepatocellular carcinoma-targeting group, was covalently decorated on the surface of MSN via an amido bond. The...

In this study, a series of mesoporous silica nanoparticle (MSN) was successfully synthesized using different ionic liquids (ILs) as template. Five ILs and surfactant with alkyl side chains types anion namely 1-dodecyl-3-methylimidazolium iodide ([C12mim][I]), 3-diethylamino propanol vanillate (DV), 2-butylamino ethanol salicylate (BS), (DS), 1-butyl-3-methylimidazolium bis(trifluoromethylsulfon...

The basal ganglia are a crucial brain system for behavioral selection, and their function is disturbed in Parkinson's disease (PD), where neurons exhibit inappropriate synchronization and oscillations. We present a spiking neural model of basal ganglia including plausible details on synaptic dynamics, connectivity patterns, neuron behavior, and dopamine effects. Recordings of neuronal activity ...

Fig. 1 Let ABCD be a circumscribed quadrilateral, that is, a quadrilateral which has an incircle. Let this incircle have the centerO and the radius ρ and touch its sides AB, BC, CD, DA at the points X, Y, Z, W, respectively. Then, for some very obvious reasons, OX ⊥ AB, OY ⊥ BC, OZ ⊥ CD, OW ⊥ DA and OX = OY = OZ = OW = ρ. Moreover, AW = AX, BX = BY, CY = CZ, DZ = DW, since the two tangents from...

Let P = f" + (I ,,) , the direct sum of the p x p identity matrix and the negative of the q x q ident ity matrix. The fo llowing theorem is proved. TH EOHEM: If X = cZ where Z is a 4 x 4 P-orthogonal , P-skew-symmetric matrix and Ie I .;;; 2, there exist matrices A an.d B, both of which are P-orthogollal and P-skew-symmetric, sach that X = AB BA. Methods for o btaining certain matrices which sa...

Enzyme immunoassays for the detection of chlamydial antigens are commonly used to diagnose Chlamydia trachomatis infection. As is true for all nonculture methods, the specificities of these tests are a concern. A confirmatory blocking assay (Abbott Laboratories, North Chicago, Ill.) was evaluated at four sexually transmitted disease test sites. This assay is designed to confirm true-positive Ch...

Mesoporous silica nanoparticles (MSNs) have been synthesized and loaded with both aluminum chloride phthalocyanine (AlClPc) and cisplatin as combinatorial therapeutics for treating cancer. The structural and photophysical properties of the MSN materials were characterized by different spectroscopic and microscopic techniques. Intracellular uptake and cytotoxicity were evaluated in human cervica...

1 Fig. 1. Galaxies in the sample PPS2: 4+1 diagram, i.e. 4 sections of (α, δ, cz; M Z) space + 1 redshift distribution histogram. Each dot is a galaxy. The redshift scale is the same everywhere. Top left: red-shift space, δ–cz wedge diagram. Top right: sky–view, α–δ diagram. Bottom right: redshift space, α–cz wedge diagram. Bottom left: dis-tance–luminosity diagram in the cz–M Z plane (the lowe...

Multidrug resistance (MDR) is the major clinical obstacle in the management of cancer by chemotherapy. Overexpression of ATP-dependent efflux transporter P-glycoprotein (PGP) is a key factor contributing to multidrug resistance of cancer cells. The purpose of the present study was to use the endosomal pH-sensitive MSN (mesoporous silica nanoparticles; MSN-Hydrazone-Dox) for controlled release o...