BACKGROUND AND METHODOLOGY This observational study aimed to establish prevalence of high-risk human papillomaviruses (hrHPV) in women attending three inner London community clinics for routine screening and to pilot hrHPV testing in the triage of either borderline or negative cytology after previous abnormalities. Hybrid Capture 2 was carried out on brush samples taken alongside conventional s...

In a prospective study we compared the diagnostic accuracy of endoscopic fine needle aspiration cytology with that of brush cytology and forceps biopsy in relation to gross tumour pattern and site in 265 confirmed consecutive cases of malignancy of the oesophagus, stomach, colon, and rectum. Aspiration cytology gave the highest diagnostic accuracy (94%), which was significantly better than that...

OBJECTIVE To determine the diagnostic accuracy of ultrasound guided fine needle aspiration (FNA) cytology and core needle biopsy (CNB) of axillary lymph nodes pre-operatively in newly diagnosed operable primary breast cancer. METHODS An observational study for all patients who underwent pre-operative FNA cytology or CNB during September 2013-August 2014 was conducted at our institution (Count...

BACKGROUND Cervical cancer prevention using cervical cytology is insufficiently sensitive, a significant proportion of HPV-infected women having normal cytology. The objective of the present study was to try to identify factors associated with abnormal cytology in HPV-infected women living in remote areas of French Guiana. METHODS A study was conducted in women aged 20-65 years having HPV inf...

OBJECTIVE The objective of the study was to compare 9 cervical cancer screening strategies to the current screening standard (cytology with human papillomavirus [HPV] triage of atypical squamous cells of undetermined significance) for the detection of high-grade cervical disease. STUDY DESIGN Women (n = 34,254) aged 30 years or older from the Addressing the Need for Advanced HPV Diagnostics (...

BACKGROUND This study aimed to better understand the supporting role that mutational profiling (MP) of DNA from microdissected cytology slides and supernatant specimens may play in the diagnosis of malignancy in fine-needle aspirates (FNA) and biliary brushing specimens from patients with pancreaticobiliary masses. METHODS Cytology results were examined in a total of 30 patients with associat...

OBJECTIVE To compare the accuracy of liquid based cytology using the computerised ThinPrep Imager with that of manually read conventional cytology. DESIGN Prospective study. SETTING Pathology laboratory in Sydney, Australia. PARTICIPANTS 55,164 split sample pairs (liquid based sample collected after conventional sample from one collection) from consecutive samples of women choosing both t...

Numerous tools and techniques such as vital stain, autofluorescence, exfoliative cytology, histomorphometry, etc. were explored in the detection of dysplasia, but have variable sensitivity specificity. The present study evaluated effect toluidine blue increasing accuracy histomorphometry analysis dysplasia OPMDs on cytology. An experimental, observational, cross-sectional research was performed...

The present study aimed to investigate the efficiency of exfoliative cytology by correlating the clinical lesions of oral squamous cell carcinoma (OSCC) with exfoliative cytology and histopathological findings. Cases of OSCC diagnosed between 1984 and 2010 were analyzed. The inclusion criteria for the present study were the availability of detailed clinical findings and a diagnosis of the disea...

Background: Fine-needle aspiration (FNA) is an effective and safe procedure for analyzing salivary gland lesions. Various morphological and overlapping cytomorphology features can bring difficulty in diagnosis of the salivary gland lesions. This study aimed to evaluate the diagnostic accuracy of fine needle aspiration cytology of salivary glands lesions. Methods: There were 107 cases of cytolog...