Objective. To investigate the effect of castration, bromocriptine and cyproterone acetate treatment on lysosomal hydrolytic enzymes and ultrastructure of the rat Harderian gland. Methods. Groups of rats were subjected to the treatment by bromocriptine, cyproterone acetate and castration. Harderian glands were dissected from each experimental animal, cut into small pieces and immediately stored ...

Based on the local Shannon entropy concept in information theory, a new measure of aromaticity is introduced. This index, which describes the probability of electronic charge distribution between atoms in a given ring, is called Shannon aromaticity (SA). Using B3LYP method and different basis sets (6-31G**, 6-31+G** and 6-311++G**), the SA values of some five-membered heterocycles, C(4)H(4)X, a...

A new formulation of a pose refinement technique using “active” models is described. An error term derived from the detection of image derivatives close to an initial object hypothesis is linearised and solved by least squares. The method is particularly well suited to problems involving external geometrical constraints (such as the ground-plane constraint). We show that the method is able to r...

Four fundamental physical parameters of series of benzene derivatives were studied to ascertain correlations with biological activity. These included octanol/water coefficient, vapor pressure, infrared absorption (out-of-plane C-H vibration), and the pi values. Each physicochemical constant exhibited a partial correlation with biological activity suggesting that each played a role. It was presu...

where most of the results presented here were obtained.

Acid-catalysed, '3+3' condensation of m-bispyrryl benzene derivatives with acetone afforded new non-aromatic macrocycles that can be converted to meso-alkylidenyl dibenzohexaphyrins carrying four exocyclic double bonds at meso-positions by DDQ oxidation.

ERDAL DINÇ1*, FATIH KAS 1, DUMITRU BALEANU2,3,4 1Ankara University, Faculty of Pharmacy, Department of Analytical Chemistry, 06100 Tandogan, Ankara, Turkey 2 Çankaya University, Faculty of Arts and Sciences, Department of Mathematics and Computer Science, 06530 Balgat,Ankara,Turkey 3 Institute of Space Sciences, Magurele-Bucharest, P.O. Box, MG-23, R 76911, Romania 4 Faculty of Engineering,King...

Modified triplex-forming oligonucleotides distinguish 5-methyl cytosine from unmethylated cytosine in DNA duplexes by differences in triplex melting temperatures. The discrimination is sequence-specific; dramatic differences in stabilisation are seen for CpA methylation, whereas CpG methylation is not detected. This direct detection of DNA methylation constitutes a new approach for epigenetic a...

In this paper, we first present a new lattice-based PKE scheme on SIS, proving that it achieves CPA-security under DBi-ISIS assumption. Compared to some lattice-based schemes, ours has some advantages and is quite efficient as well as great simplicity. Similarly, we give a lattice-based PKE with multiple bits which is CPA secure under DBi-ISIS assumption. We hope that our contributions help to ...