Cyanosis is a common physical sign in clinical medicine. Cardiac or respiratory conditions are the usual causes. We report a patient with an unusual cause for cyanosis and highlight the salient clues that lead to the diagnosis.

the relationship between congenital heart disease (chd) and growth retardation is well documented. we investigated the growth condition of iranian children with several types of congenital heart disease (chd) and compared it with worldwide researches. growth condition was investigated in 469 patients with important chd aged from 1 month to 18 years. the patients were divided into two groups; in...

Two young women had unexpected cyanosis a few hours after cardiac catheterisation for electrophysiological investigation. The first patient had atrioventricular septal defect, had undergone repeated surgical interventions, and was referred because of atrial flutter. The second patient had ablation of an accessory pathway in Wolff-Parkinson-White syndrome. Local anaesthesia was performed with 40...

It is known that the presence or absence of cyanosis of warm parts is some guide to the level of arterial oxygen saturation. Comroe and Botelho (1947) exposed the limitations of cyanosis as a sign, but their observations were made in bright light on normal subjects, who inhaled decreasing percentages of oxygen in nitrogen. Some sites commonly used for the detection of central cyanosis, such as ...

OBJECTIVES It is controversial whether immature cyanotic hearts are more susceptible to ischemic injury than normoxemic hearts. Acutely induced alveolar hypoxic stress before cardiopulmonary bypass has been used as a model of cyanosis and is reported to worsen recovery of immature hearts after subsequent ischemic insult by means of a free radical injury mechanism. Because of concerns about the ...

Sulfhemoglobinemia is a rare condition in which a sulfur atom oxidizes the heme moiety in hemoglobin, making the hemoglobin incapable of carrying oxygen and leading to hypoxia and cyanosis. This condition has been described in patients taking sulfur medications or who have cultured hydrogen sulfide producing intestinal bacteria such as Morganella morganii. This case describes a pediatric patien...

Neonatal cyanosis in healthy newborns can be associated either with methemoglobin due to cytochrome b5 reductase deficiency or to M-hemoglobin, a group of hemoglobin variants resulting from mutations in the globin chain genes. We report the clinical case of a neonate with cyanosis and normal cardiac and respiratory function. At birth the hematological parameters were normal; however, the methem...

The infant presenting to the emergency department with cyanosis requires rapid assessment, diagnosis, and initiation of therapy. In this article, the potential challenges in recognizing cyanosis are discussed, including the presence of higher concentrations of fetal hemoglobin, and its oxygen binding characteristics. A systematic approach to the diagnosis of cyanosis is presented, based on an u...

abstractthe valves of right horn of systemic venous sinus are prominent structures within the right atrium during early embryonic period. involution of these structures may not be complete, resulting in a spectrum of anatomical presentations such as cyanosis. a full-term male neonate referred to our hospital for precise evaluation of severe cyanosis on the first day of life. echocardiographic e...

Background: CKMB, the cardiac-specific heterodimer of cytosolic creatine-kinase (CK), is developmentally and physiologically regulated, tissue hypoxia being a proposed regulator. In patients with cyanotic heart disease the myocardium is perfused with partially saturated blood. We questioned whether the myocardium of cyanotic subjects contains higher proportions of CKMB. Materials and Methods: C...