نتایج جستجو برای: cutaneous atrophy
تعداد نتایج: 90483 فیلتر نتایج به سال:
Case presentation: JRCS, female, started, at 15 years old, dysphagia initially for solids, progressing to liquids, hand dystonia and anarthria after isolated fever. At the time she was admitted another pediatric center diagnostic investigation, with normal brain MRI, EEG ENMG. History of mother undiagnosed psychiatric disorder progressive gait dysfunction. age 16 hospitalized malnutrition assoc...
The aim of this study was to investigate whether stimulation of the cutaneous mechanoreceptors of the rat foot sole could partially or totally prevent the soleus muscle atrophy developed after 14 days in hindlimb unloading conditions. Final experiments were achieved under deep anesthesia using pentobarbital sodium (60 mg/kg, ip injection). Atrophy was characterized by a significant decrease in ...
One of the major adverse effects of topical glucocorticoids is cutaneous atrophy often followed by development of resistance to steroids (tachyphylaxis). Previously we showed that after two weeks, interfollicular mouse keratinocytes acquired resistance to anti-proliferative effects of glucocorticoid fluocinolone acetonide (FA). One of the top genes activated by FA during tachyphylaxis was Klk6 ...
Radical cystectomy, as the most common surgical treatment for patients with invasive bladder cancer (IBC) complicated by peritoneal metastasis, is usually accompanied by a urinary diversion procedure. In this study, we evaluated the improved tubeless cutaneous ureterostomy technique by comparing the resulting clinical effects with either a traditional ureterostomy and an ileal conduit urinary d...
Gynecomastia, cutaneous spider nevi, testicular atrophy, and loss of libido are frequently found in men with chronic liver disease. The clinical aspects of the subject have recently been reviewed (1). On the basis of studies of urinary estrogen excretion (2), these changes have been attributed to increased levels of estrogens, particularly unconjugated estrogens presumably resulting from decrea...
Dyskeratosis congenita and Fanconi’s anemia share impressive features in common: primary refractory pancytopenia; bone marrow hyperplasia (curtailed phase) and megaloblastosis, eventuating in severe hypoplasia of the marrow; cutaneous melanotic dyschromia; lacrimal duct blockage and a host of other minor abnormalities, in addition to mental retardation and generalized impairment of growth. Eval...
Background. It is often difficult to differentiate Parkinson's disease (PD) from multiple system atrophy (MSA), especially in their early stages. Objectives. To examine the clinical utility of histopathological analysis of biopsied skin from the chest wall and/or leg in differentiating between the two diseases. Methods. Skin biopsies from the lower leg and/or anterior chest wall were obtained f...
Multiple asymptomatic cutaneous pilar leiomyoma versus spontaneous eruptive keloids - a case report.
Cutaneous piloleiomyoma, angioleiomyoma and genital leiomyoma are variants of superficial cutaneous leiomyoma. The main purpose of this paper was to present clinical, histopathological and immunohistochemical diagnosis criteria for an unusual case of pilar leiomyoma in an 18-year-old male patient. The initial clinical aspect was very similar to spontaneous eruptive keloids: red-violet color, pa...
The skin is not an inert covering but a sensitive dynamic boundary. In addition to disorders that primarily affect the skin, most of the major systemic diseases have cutaneous manifestations (1). Skin is the most visible and easily accessible organ of the body. It is a mirror for many systemic diseases including renal diseases (2). The protean cutaneous manifestations of renal disease are prima...
OBJECTIVE To develop and assess the psychometric properties of the Localized Scleroderma (LS) Skin Damage Index (LoSDI) and Physician Global Assessment of disease Damage (PGA-D). METHODS Damage was defined as irreversible/persistent changes (>6 months) due to previous active disease/complications of therapy. Eight rheumatologists assessed the importance of 17 variables in formulating the PGA-...
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