Kroneck et al. [(1988) FEBS Lett. 242, 70-74] have recently suggested, on the basis of a comparison with the EPR properties of nitrous oxide reductase, that cytochrome c oxidase contains a mixed-valence binuclear copper site, and that this is responsible for the EPR spectrum generally ascribed to CuA. Here we question this hypothesis in view of a multitude of analytical and spectroscopic data a...

Calcific uremic arteriolopathy (CUA), also referred to as calciphylaxis, is a syndrome of small vessel calcification of unknown etiology causing painful violaceous skin lesions that progress to non-healing ulcers and gangrene. It is observed mainly in patients with end-stage renal disease, is associated with high morbidity and mortality and has no standard treatment at the present time. Althoug...

Meiatermes cretacicus n. sp., an alate termite from the Early Cretaceous Crato Formation, Araripe Basin, northeastern Brazil. The new taxon is similar in many characteristics to other termites and primitive Spanish amber. rounded head pronotum, Y-shaped line, veins Sc, R, Rs M more heavily sclerotized than CuA, multiple branches, CuA well-developed are features shared with basal-most belonging ...

This paper describes a framework for developing applications that conform to Systems Application Architecture (SAA). The paper shows a high-level approach to creating a design; it gives examples of early modeling work with the user interface; and it appraises SAA through the eyes of several system designers. The usability of user interfaces has been evaluated through the modeling of office task...