This article discusses a hot topic on double low-dose protocol of computed tomography pulmonary angiography (CTPA) in the diagnosis of pulmonary embolism, with a special focus on a recent paper published in the British Journal of Radiology about the feasibility of this technique. Three aspects will be discussed in this review: First, both kVp and contrast medium can be reduced without affecting...

Aim Pulmonary embolism (PE) is a known cause of morbidity and mortality in oncology patients. Whilst much of the literature focuses on the detection of incidental PE in this cohort of patients (approximately 4%), little is written about the rate of positive CT Pulmonary Angiograms (CTPA) when PE is clinically suspected. We wanted to assess the rate of positive CTPA specifically amongst oncology...

Zhonghua Sun1* and Jing Lei2 1Department of Medical Radiation Sciences, Curtin University, Perth, Western Australia, 6845, Australia 2Department of Medical Imaging, First Affiliated Hospital of Kunming Medical University, Yunnan, 650032, China *Author for correspondence: Tel: +61892667509 Fax: +61892662377 E-mail: [email protected] Submitted: August 18, 2017 Accepted: September 13, 2017 Publi...

OBJECTIVE To investigate whether fast grading of reflux of contrast to the inferior vena cava (IVC) on computerized tomographic pulmonary angiography (CTPA) is a potential biomarker for real-time risk stratification. METHODS We retrospectively identified 343 patients investigated for possible pulmonary embolism (PE) by CTPA at our medical center between September 2004 and March 2006. A total ...

Post-translational modification expands the functionality of the proteome beyond genetic encoding, impacting many cellular processes. Cleavage of the carboxyl terminus is one of the many different ways proteins can be modified for functionality. Gel-electrophoresis and mass spectrometric-based techniques were used to identify proteins impacted by deficiency of a C-terminal protease, CtpA, in Rh...

LESS ISMORE Computed Tomographic Pulmonary Angiography: Clinical Implications of a LimitedNegative Result A substantial proportion of computed tomographic pulmonary angiography (CTPA) results are degraded by patientrelated and technical factors, yielding a limited negative interpretation, which qualifies the definitive exclusion of pulmonaryembolism.This leads todiagnosticuncertaintyand may aff...

The clinical diagnosis of acute pulmonary embolism (PE) is frequently considered in patients presenting to the emergency department or when hospitalized. Since symptoms are a-specific and the consequences of anticoagulant treatment are considerable, objective tests to either establish or refute the diagnosis have become a standard of care. Computed tomographic pulmonary angiography (CTPA), whic...

In patients with suspected pulmonary embolism, posterior/anterior and lateral chest X-rays are recommended as an initial imaging examination because they may reveal an alternate diagnosis and obviate the need for further imaging. If the chest X-ray is negative and the patient has a D-dimer level over an age-adjusted threshold, CT pulmonary angiography (CTPA) is the examination of choice. Ventil...

HYPOTHESIS Spiral computed tomographic pulmonary angiography (CTPA) is sensitive and specific in diagnosing pulmonary embolism (PE) in critically ill surgical patients. DESIGN Prospective study comparing CTPA with the criterion standard, pulmonary angiography (PA). SETTING Surgical intensive care unit of an academic hospital. PATIENTS Twenty-two critically ill surgical patients with clini...

To assess the value of three-dimensional (3D) contrast-enhanced (CE) magnetic resonance pulmonary angiography (MRPA) with liver acceleration volume acquisition (LAVA) in the detection of acute pulmonary embolism (PE). Thirty-two patients with symptoms indicative of acute PE underwent both CT pulmonary angiography (CTPA) and MRPA within 4 hours. Three of the patients were excluded from the final...