In this study, we evaluated the association between high-risk human papillomavirus (hrHPV) and the vaginal microbiome. Participants were recruited in Nigeria between April and August 2012. Vaginal bacterial composition was characterized by deep sequencing of barcoded 16S rRNA gene fragments (V4) on Illumina MiSeq and HPV was identified using the Roche Linear Array® HPV genotyping test. We used ...

Objectives: Corticospinal tract (CST) is the most important tract in motor control. However, there was no study about the change of CST location with aging. In this study, using diffusion tensor tractography (DTT), we attempted to investigate the change of CST location at cortex, corona radiata (CR) and posterior limb of internal capsule (IC) level with aging in typically developing children. M...

BACKGROUND AND PURPOSE Aside from the primary motor cortex, the corticospinal tract (CST) also receives fibers from dorsal and ventral premotor cortices and supplementary motor area, all of which might potentially contribute to motor function after stroke. We sought to quantify the microstructural integrity of CST originating from the hand representations in these 4 motor cortices separately an...

BACKGROUND Smoking has been identified in observational studies as a risk factor for bacterial vaginosis (BV), a condition defined in part by decimation of Lactobacillus spp. The anti-estrogenic effect of smoking and trace amounts of benzo[a]pyrene diol epoxide (BPDE) may predispose women to BV. BPDE increases bacteriophage induction in Lactobacillus spp. and is found in the vaginal secretions ...

Abstract Introduction Simulation is increasingly being used to augment clinical experience. However, access simulation varies geographically and national courses can be costly. The Severn School of Surgery aimed provide a locally run, cost-neutral “Basic Principles in Fracture Fixation” course standardise for core surgical trainees (CSTs). Method ran from district general hospital, accommodatin...

The suffix tree is a very important data structure in string processing, but it suffers from a huge space consumption. In large-scale applications, compressed suffix trees (CSTs) are therefore used instead. A CST consists of three (compressed) components: the suffix array, the LCP-array, and data structures for simulating navigational operations on the suffix tree. The LCP-array stores the leng...

Preterm birth (PTB) is a significant health problem globally, with an estimate of 15 million cases annually. Approximately 10% neonates born early will die prematurely, while subset develop severe life-long morbidities. Unfortunately, preterm birth’s syndromic nature has evaded prevention strategies, and it continues to impose high burden on healthcare systems families. The role vaginal bacteri...

Objectives Stress and burn-out among surgical trainees has been reported most prevalent in core (CST) female particular. This study aimed to identify factors perceived by CSTs be associated with stress burnout those at risk. Design An open-ended questionnaire was distributed 79 two researchers categorised responses independently, according Michie’s model of workplace stress. Setting A UK region...

Client-focused research systems have been developed to monitor and provide feedback information about clients’ progress in psychotherapy as a method of enhancing outcome for those who are predicted to be treatment failures. In the current study, the authors examined whether feedback regarding client progress and the use of clinical support tools (CSTs) affected client outcome and number of sess...