The susceptibility of human lens aldose reductase (HLAR), human placental aldose reductase (HPAR), and rat lens aldose reductase (RLAR) to inhibition by 10 structurally diverse inhibitors is compared. Significant differences in the susceptibility of these enzymes was observed; however, no trends could be predicted. In general, HPAR appeared to be less susceptible to inhibition than either HLAR ...

1 The Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia, 2 Department of Health Services Research, CAPHRI, Faculty of Health, Medicine and Life Sciences, Maastricht University Medical Centre, Maastricht University, Maastricht, Netherlands, 3 Top Institute Evidence-Based Education Research (TIER), Maastricht University, Maastricht, Netherlands, 4 Faculty of Social and Pol...

We present the selection of the Jodrell Bank Flat-spectrum (JBF) radio source sample, which is designed to reduce the uncertainties in the Cosmic Lens All-Sky Survey (CLASS) gravitational lensing statistics arising from the lack of knowledge about the parent population luminosity function. From observations at 4.86 GHz with the Very Large Array, we have selected a sample of 117 flat-spectrum ra...

The gradient refractive index of the crystalline lens in the Black Oreo Dory (Allocyttus Niger) was determined using two methods; an optimisation program based on finite ray-tracing and the path of laser beams through the lens, and magnetic resonance imaging (MRI) and the linear relationship between refractive index and nuclear transverse relaxation rates. The methods showed good agreement in t...

An optical coherence tomography system has been developed that was designed specifically for imaging the isolated crystalline lens. Cross-sectional OCT images were recorded on 40 lenses from 32 human donors with an age range of 6-82 years. A method has been developed to measure the axial thickness and average refractive index of the lens from a single recorded image. The measured average group ...