Quantitative histology of the descended testis of unilateral cryptorchid bucks was compared with testis of normal bucks to evaluate the reproductive potentials of the scrotal testis in unilateral cryptorchids, using light microscopy techniques. The contralateral scrotal testes of the unilateral cryptorchids and the testes of the normal bucks contained profiles of seminiferous epithelium and eac...

The failure of testicular descent or cryptorchidism is the most common defect in newborn boys. The descent of the testes during development is controlled by insulin-like 3 peptide and steroid hormones produced in testicular Leydig cells, as well as by various genetic and developmental factors. While in some cases the association with genetic abnormalities and environmental causes has been shown...

An 11-year-old male German Shepherd dog presented for inappetence and weight loss. Physical examination and initial bloodwork revealed palpable abdominal masses, mild non-regenerative anemia, and thrombocytopenia. Survey radiography and abdominal ultrasonography confirmed the presence of bilateral abdominal masses and lymphadenopathy. Contrast-enhanced computed tomography (CT) was performed in ...

To investigate the mechanism of spermatogenesis arrest derived from heat treatment and to screen temperature-related genes involved in spermatogenesis, the authors analyzed the differences in gene expression between cryptorchid and scrotal testes in rats, and cloned a full-length cDNA named TRS1. In situ hybridization showed that TRS1 mRNA was mainly expressed in spermatocyte and round spermati...

In recent years novel information about the hormonal regulation of testicular descent has emerged from genetically modified mice and other experimental animal models with cryptorchid phenotypes. We have studied transgenic (TG) mice overexpressing P450 aromatase (AROM+) and insulin-like 3 (INSL3+), and knockout (KO) mice for the genes of LH receptor (R) (LuRKO) and the thyroid-specific enhancer/...

The development of testes occurs in the abdomen during fetal life, after which they migrate into the scrotal sacs during the third trimester. During their descent, they may get arrested anywhere along the tract. Risk of testicular cancer is higher in patients with undescended testes, abdominal testis being more prone than inguinal. Seminoma is the commonest cancer in undescended testis. However...

OBJECTIVE The cryptorchidism is a risk factor for testicular cancer and is associated with cancer in the contraleteral testicle. The mechanism that leads to an increased risk of causes in a cryptorchid testis is unclear. MATERIALS AND METHODS We analyzed 25 patients of 20-years old for maldescended testicles we practiced orchiectomy in 22 testicles and orchiopexy in 7 testicles. The time pati...

PURPOSE We dissected prevailing assumptions about cryptorchidism and reviewed data that support and reject these assumptions. MATERIALS AND METHODS Five questions about cryptorchidism and the risk of testicular cancer were identified because of their implications in parent counseling and clinical management. Standard search techniques through MEDLINE were used to identify all relevant English...

Several clinicopathological illnesses impact the testis and paratesticular area, which are divided into non-neoplastic neoplastic diseases. Despite availability of imaging tumor marker testing, histopathological examination is primary method for diagnosing testicular lesions. Common indications orchidectomy lesions cryptorchidism, epididymitis torsion. Few non- present as mimickers neoplasm wit...