In an observer blind comparative study, 130 men with penile warts were randomly allocated to treatment with either cryotherapy or trichloroacetic acid (TCAA). There was no significant difference in response to treatment, side effects, or recurrence rates between the two treatments. Warts resolved in 81% of patients treated with TCAA compared with 88% of those treated with cryotherapy. Early rec...

background and purpose: pain perception with arteriovenous fistula (avf) cannulation is a major concern among patients undergoing hemodialysis. this study aimed to compare the efficacy of cryotherapy and placebo in the reduction of avf puncture-related pain in hemodialysis patients. methods: this randomized clinical trial was conducted on 50 patients undergoing hemodialysis selected via random ...

BACKGROUND In low-resource settings, cryotherapy can be cost-effective, affordable, and a first-line treatment for cervical intraepithelial neplasia (CIN) of any grade. OBJECTIVES To report the acceptability, safety and effectiveness of cryotherapy for women with cervical intraepithelial neoplasia (CIN) in Western Kenya. METHODS Visual inspection with acetic acid (VIA)-positive women and th...

Background: Although cryotherapy is still the first-line therapy for solar lentigines, due to side effects such as post-inflammatory hyperpigmentation (PIH), especially in patients with darker skin types, pigment specific lasers should be considered as initial treatment. The aim of this study was to evaluate the efficacy and safety of cryotherapy in comparison with 595-nm pulsed dye laser (PDL)...

Background: Cryotherapy is one of the most popular electro-physical agents used to ‘treat’ acute inflammation after a soft tissue injury. Much of the clinical rationale for this is based on anecdotal reports, with most clinicians accepting that cryotherapy has an ‘anti’ inflammatory effect after injury. There have been a number of recent advances towards improving our understanding of the infla...

PURPOSE To report a case series of conjunctival lymphangiectasia treated with liquid nitrogen cryotherapy. METHODS A 1.5-mm Brymill cryoprobe was applied in a double freeze-thaw method after an incisional biopsy of a portion of the conjunctiva in patients with conjunctival lymphangiectasia. Freeze times were 1 to 2 seconds with thawing of 5 to 10 seconds between treatments. Patients were reex...

OBJECTIVE To determine the effect of cryotherapy on HIV-1 cervical shedding. DESIGN Prospective cohort study. METHODS Five hundred HIV-positive women enrolled at an HIV treatment clinic in Nairobi, Kenya were screened for cervical cancer. Women diagnosed with cervical intraepithelial neoplasia stage 2 or 3 (CIN 2/3) by histology were offered cryotherapy treatment. The first 50 women had cer...

Cryotherapy refers to the use of cold temperature to treat disease and is a mainstay therapeutic modality for a wide variety of skin conditions. This article reviews the early history of development of cryotherapy in dermatology.

REASONS FOR PERFORMING STUDY A previous preliminary study demonstrated the potential of distal limb cryotherapy (DLC) for preventing laminitis. Clinically, DLC must be effective for periods longer than 48 h and the preventive effect must extend beyond its discontinuation. OBJECTIVES To evaluate the effect of DLC, applied during the developmental phase of induced laminitis, on the severity of ...

OBJECTIVES Keloid and hypertrophic scars are abnormal manifestations of wounds that occur following skin injuries in the form of local proliferation of fibroblasts and increased production of collagen. There are several ways to cure these scars; treatment must be selected based on the nature of the scars. In this clinical trial, two methods-cryotherapy and intense pulsed light (IPL)-are compare...