نتایج جستجو برای: crush

تعداد نتایج: 2955  

Journal: :The Annals of otology, rhinology, and laryngology 2008
Belachew Tessema Michael J Pitman Rick M Roark Craig Berzofsky Sansar Sharma Steven D Schaefer

OBJECTIVES We developed a standardized method of minimally invasive transoral laryngeal (ToL) bipolar electromyography (EMG) for evaluation of recurrent laryngeal nerve (RLN) recovery after a controlled crush injury in a rat model. METHODS Ten 200- to 250-g Sprague-Dawley rats underwent a controlled crush injury to the left RLN performed with 60 seconds of use of a calibrated aneurysm clamp w...

Journal: :Emergency nurse : the journal of the RCN Accident and Emergency Nursing Association 2003
Keith Porter Ian Greaves

Crush syndrome remains rare in European practice but is common in areas of civil disorder and where society has given way to civil war or natural disaster. Clinicians in the west are becoming increasingly involved in such situations and there is no reason to believe that the few instances due to conventional causes, such as an elderly person collapsing or road traffic accidents, will cease. The...

Journal: :Investigative ophthalmology & visual science 1998
L A Levin K M Geszvain

PURPOSE To better understand the molecular program of neuronal cell death induced by axotomy, the authors attempted to identify retinal genes differentially expressed by optic nerve crush. METHODS Total RNA isolated from rat retinas at 1 and 4 days after intraorbital optic nerve crush was used in a modification of the differential display technique. After several rounds of screening, a single...

Journal: :Investigative ophthalmology & visual science 2006
Tomomi Higashide Ichiro Kawaguchi Shinji Ohkubo Hisashi Takeda Kazuhisa Sugiyama

PURPOSE To determine whether a scanning laser ophthalmoscope (SLO) is useful for in vivo imaging and counting of rat retinal ganglion cells (RGCs). METHODS RGCs of Brown Norway rats were retrogradely labeled bilaterally with the fluorescent dye 4-(4-(dihexadecylamino)styryl)-N-methylpyridinium iodine (DiA). The unilateral optic nerve was crushed intraorbitally with a clip. RGCs were imaged in...

Journal: :Investigative ophthalmology & visual science 2007
Ken-ichiro Miyake Miho Yoshida Yoshitsugu Inoue Yoshio Hata

PURPOSE Traumatic optic neuropathy often induces a loss of vision that proceeds rapidly within several hours, together with retinal ganglion cell death, in a much slower time course. Electrical stimulation has previously been shown to rescue injured retinal ganglion cells from cell death. The present study tests whether transcorneal electrical stimulation could preserve visual function after an...

Journal: :Investigative ophthalmology & visual science 2004
Kazumi Maeda Akira Sawada Masayuki Matsubara Yoshiyuki Nakai Akira Hara Tetsuya Yamamoto

PURPOSE To investigate the effects of repeated treatments with a neuroprotective compound, R(-)-1-(benzo [b] thiophen-5-yl)-2-[2-(N, N-diethylamino) ethoxy] ethanol hydrochloride (T-588), on retinal ganglion cell (RGC) survival in rat eyes with elevated intraocular pressure (IOP) or after optic nerve crush. METHODS An increase in IOP was induced by a single laser treatment to the trabecular m...

Journal: :JACC. Cardiovascular interventions 2013
Kari Kervinen Matti Niemelä Hannu Romppanen Andrejs Erglis Indulis Kumsars Michael Maeng Niels R Holm Jens F Lassen Pål Gunnes Sindre Stavnes Jan S Jensen Anders Galløe Inga Narbute Dace Sondore Evald H Christiansen Jan Ravkilde Terje K Steigen Jan Mannsverk Per Thayssen Knud Nørregaard Hansen Steffen Helqvist Saila Vikman Rune Wiseth Jens Aarøe Jari Jokelainen Leif Thuesen

OBJECTIVES The aim of the study was to compare long-term follow-up results of crush versus culotte stent techniques in coronary bifurcation lesions. BACKGROUND The randomized Nordic Stent Technique Study showed similar 6-month clinical and 8-month angiographic results with the crush and culotte stent techniques of de novo coronary artery bifurcation lesions using sirolimus-eluting stents. Her...

2014
Petr Dubový Ilona Klusáková Ivana Hradilová Svíženská

Activated Schwann cells distal to nerve injury upregulate inflammatory mediators, including cytokines. The goal of the present study was to investigate expression of proinflammatory (IL-1β, TNFα) and anti-inflammatory cytokines (IL-4, IL-10) in activated Schwann cells in relation to growing axons distal to crush injury of rat sciatic nerves. Seven days from sciatic nerve crush, transverse cryos...

Journal: :Brain research 1982
S Kohsaka A M Heacock P D Klinger R Porta B W Agranoff

The significance of a previously observed increase in retinal ornithine decarboxylase (ODC, EC 4.1.1.17) following optic nerve crush was investigated in goldfish using a specific irreversible inhibitor of ODC, alpha-difluoromethylornithine (DFMO). Retinal ODC activity and putrescine levels were reduced 80% and 40%, respectively, by intraperitoneal injection(s) of DFMO. In fish in which the righ...

2009
Wenfang Li Jun Qian Xuefen Liu Qiang Zhang Lv Wang Dechang Chen Zhaofen Lin

INTRODUCTION The experience on management of crush injury after a devastating earthquake is lacking, and there are even less reports on the front-line critical care of these patients. A front-line intensive care unit (ICU) was set up in a tent after the disastrous Wenchuan earthquake (May, 12, 2008, China), where 32 patients suffering from crush injury were treated from May 12 to May 26. This s...

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