buthotus schach is one of the dangers scorpion in iran that belong to the buthidae family. toxins are existing in venom scorpion, modulate the ion channels by blocking or opening the pore of the channel or by altering the voltage gating and useful as pharmacological tools. in the present study, we investigated the effect of venom and its obtained fractions by gel filtrations on electrophysiolog...

BACKGROUND Scorpions stings are a health problem in many parts of the world. Mesobuthus eupeus (Buthidae) is the most prevalent species in the Middle East and Central Asia. Definition of toxicogenic and immunogenic characteristics of the venom is necessary to produce antidote. In this study, the noted properties of M. eupeus venom were evaluated. METHODS Venom was obtained by milking M. eupeu...

snake venoms contain a rich variety of factors which affect blood coagulation. there have been few reports on the anticoagulant activity of the venom of different cobras, but no such observations have been made on the iranian cobra, although a procoagulant factor has been described. in this study an anticoagulant factor has been purified from the venom of naja naja oxiana using gel filtration f...

background: cutaneous reactions like pruritus and erythema are common in warm months of the year in bushehr port, persian gulf, iran due to jellyfish envenomation. this study reports isolation of the chrysaora hysoscella nematocysts and evaluating its pharmacological activities during a bloom in 2013. methods: the venom of c. hysoscella captured in jofre area in bushehr port was analyzed. the e...

  Scorpion venoms contain of variety of peptides toxic to mammals ، insects and crustaceans. Toxic peptides are the main factors in scorpion venom causing toxicity, (their amount being 1-3%of total venom.). Most of the scorpion toxins have been isolated from the venoms of scorpions in the family Buthidae. The scorpion Buthotus Schach belonging to the Buthidae family is widely found in the weste...

Complex target SELEX always have been an intriguing approach to the scientific community, as it offers potential discovery of novel biomarkers. We herein successfully performed on Bungarus caeruleus venom develop a panel highly affine aptamers that specifically recognizes B. (common krait) and was able discriminate from Cobra, Russell's, Saw-scaled viper's venom. The generated against crude als...

This paper records for the first time the exocrine pancreatic response to scorpion venom, in this case that of Tityus trinitatis, a scorpion endemic in Trinidad. The crude venom injected intravenously into fasting anaesthetised dogs induced a secretion of the exocrine pancreas. The secretion evoked was rich in enzymes.

Objective: This study was conducted to investigate whether fractions of jellyfish Cassiope andromeda venom, could selectively induce toxicity on mitochondria isolated from cancer tissue of patients with breast adenocarcinomas. Methods: Firstly, we extracted two fractions, (f1 and f2) from crude jellyfish venom by gel filtration on Sephadex G-200.Then different dilutions of these extracted fract...

Snake venoms are composed of a complex mixture of active proteins that induce toxic effects, such as edema, hemorrhage, and death. Lachesis muta has the highest lethality indices in Brazil. In most cases, antivenom fails to neutralize local effects, leading to disabilities in victims. Thus, alternative treatments are under investigation, and plant extracts are promising candidates. The objectiv...

BACKGROUND It has been reported that biologically active compounds extracted from Cnidaria venom may induce damage by oxidative stress. Erythrocytes are constantly exposed to oxidative stresses, which can contribute to sulphydril (SH-) group oxidation and cell membrane deformability accompanied with activation of K-Cl co-transport and inhibition of anion transport. In this regard, Band 3 protei...