The prevalence and clinical impact of atrial fibrillation (AF), the most common cardiac rhythm disturbance, continues to increase. The pathophysiology of AF is still not well understood and it is generally accepted that the majority of cases are due to fibrosis or degeneration of the atrial muscle, sinus node disease or conduction abnormalities, or to the underlying heart disease itself or agei...

Background. The contribution of residual renal function (RRF) to dialysis adequacy in continuous ambulatory peritoneal dialysis (CAPD) patients is well known. The aim of our study was to evaluate the effects of RRF on various clinical and laboratory features including degree of anemia, phosphorus control, and nutritional parameters in patients on CAPD. Methods. Patients on CAPD therapy who had ...

This study aimed to explore the effective role of carnosine and /or Larginine in down regulation of the inflammatory molecule expression caused renal damage in response to sodium nitrite (NaNO2) induced hypoxia in rats . NaNO2 was administered subcutaneously (s.c.) to rats as a single dose (60 mg/kg body weight ). L-arginine (200mg/Kg body weight) and carnosine (250 mg/ Kg body weight ) were ad...

C-reactive protein (CRP) as it occurs in serum and in all but a very few pathological fluids is associated with a phosphorus-containing substance or substances of lipid character.' It can be obtained from the fraction of serum precipitable by 0.5 to 0.75 saturation with ammonium sulfate, following dialysis against dilute calcium chloride. The complex obtained by this procedure is insoluble in d...

Background: Metabolic dysregulation is a hallmark of diseases such as Type 2 diabetes, Cancer, and Cardiovascular disease (1). Purpose: In this study, we assessed whether dietary capsaicin in the form of cayenne pepper improves the risk factors of metabolic dysregulation in atherogenic diet-fed rats with inflammation. Procedure: Forty rats were divided into four groups with 50% consuming a cont...

Objective: To investigate a relationship of asthma symptoms and exacerbations with systemic (high-sensitivity Creactive protein (hs-CRP), eosinophilic cationic protein (ECP), leukocytes) and local (exhaled NO (FENO), pH and urates in exhaled breath condensate (EBC) and exhaled breath temperature (EBT)) inflammatory biomarkers (BMs) in asthmatic children. Methods: This cross-sectional study comp...

The prevalence and clinical impact of atrial fibrillation (AF), the most common cardiac rhythm disturbance, continues to increase. The pathophysiology of AF is still not well understood and it is generally accepted that the majority of cases are due to fibrosis or degeneration of the atrial muscle, sinus node disease or conduction abnormalities, or to the underlying heart disease itself or agei...

Lanza GA, Pitocco D, Navarese EP, Sestito A, Sgueglia GA, Manto A, Infusino F, Musella T, Ghirlanda G, Crea F. Istituto di Cardiologia, Università Cattolica del Sacro Cuore, Largo A. Gemelli, 8, 00168 Roma, Italy. [email protected] AIMS: To assess the relationship between cardiac autonomic dysfunction and inflammation in patients with type 1 diabetes and whether beta-blocker therapy might imp...

BACKGROUND C-reactive protein concentration has continuous associations with risk of coronary artery disease, ischemic stroke and death from several cancers. In addition, several studies have shown that CRP could be used to predict first ever myocardial infarction and stroke in healthy subjects, as well as outcome in acute setting. High levels of another biomarker, D-dimer, have been found to b...