Glycosylation of cell surface proteins can regulate multiple cellular functions. We hypothesized that glycosylation and expression of glycoproteins after epithelial injury is important in mediating repair. We report the use of an in vitro culture model of human airway epithelial cells (1HAEo(-)) to identify mediators of epithelial repair. We characterized carbohydrate moieties associated with r...

Nontuberculous mycobacterial lung disease (NTM-LD) is increasingly recognized as an important predisposing condition for the development of chronic pulmonary aspergillosis (CPA), but there are limited data on the risk factors for CPA development in NTM-LD patients. We reviewed the medical records of 566 patients who, at the time of diagnosis of NTM-LD, did not have CPA and who received ≥12 mont...

Cyclophasphamide (CPA) is used to treat various types of cancer. It is a cytotoxic alkylating agent widely used in chemotherapeutic regimen. However, the clinical efficacy of CPA is marred by its side effects. In clinical applications of CPA, it becomes necessary to prevent the oxidative stress and reproductive toxicity induced thereby in normal cells. In the present study, we investigated the ...

Control performance assessment, or CPA, is an increasingly vital tool to quantify the performance of industrial control loops. While most of the research and commercial activity in CPA has been applied to linear systems to date, those researchers investigating nonlinear systems fall into one of two groups. The first group focussed on the diagnosis of a common specific nonlinearity, namely valve...

A highly aggressive human CALLA+Cp+ pre-B acute lymphoblastic leukemia (ALL) cell line (NALM-6-UM1) causes disseminated and invariably fatal leukemia in CB.17 mice with severe combined immunodeficiency (SCID). We used this SClD mouse model of human pre-B ALL to evaluate and compare, in a total of 434 SClD mice, the antileukemic efficacy of 843 (anti-CD19)-pokeweed antiviral protein (PAP) immuno...

OBJECTIVES Chronic pulmonary aspergillosis (CPA) is an emerging complication after lobectomy for lung cancer. This retrospective study aimed to determine the incidence, main risk factors and clinical features of postoperative CPA in lung cancer patients. METHODS This study included lung cancer patients treated by lobectomy and with no previous history of thoracic surgery or coexistent aspergi...

Applications of the Covering Property Axiom Andrés Millán Millán The purpose of this work is two-fold. First, we present some consequences of the Covering Property Axiom CPA of Ciesielski and Pawlikowski which captures the combinatorial core of the Sacks’ model of the set theory. Second, we discuss the assumptions in the formulation of different versions of CPA. As our first application of CPA ...

OBJECTIVE Although the intergenerational transmission of family violence has been well documented, the mechanisms responsible for this effect have not been fully determined. The present study examined whether trauma symptoms mediate the relationship between a childhood history of child physical abuse (CPA) and adult CPA risk, and whether any such mediation was similar for women and men. METHO...

Little is known about the reliability of self-reported child physical abuse (CPA) or CPA reporting practices. We estimated reliability and prevalence of self-reported CPA and identified factors predictive of inconsistent CPA reporting among 2,256 participants using surveys administered in 1995 and 2000. Reliability of CPA was fair to moderate (kappa = 0.41). Using a positive report from either ...

Partial adenosine A1 receptor agonists with reduced intrinsic activity at the cardiovascular system would be promising for therapeutic application (e.g., as antilipolytic agents). In the present study a series of 8-alkylamino [methyl (M)-, ethyl (E)-, propyl (P)-, butyl (B)- and cyclopentyl (CP)-] derivatives of N6-cyclopentyladenosine (CPA) were investigated in conscious normotensive rats. Aft...