نتایج جستجو برای: coxsackievirus b3

تعداد نتایج: 7486  

Journal: :Cardiovascular research 2007
Yoshinori Seko Hideo Yagita Ko Okumura Miyuki Azuma Ryozo Nagai

OBJECTIVE This study was designed to investigate the roles of programmed death-1 (PD-1) and PD-1 ligands (PD-L) in the development of murine acute myocarditis caused by Coxsackievirus B3. PD-1/PD-L belong to the CD28/B7 superfamily, and the PD-1/PD-L pathway is known to transduce a negative immunoregulatory signal that antagonizes the T-cell receptor-CD28 signal and inhibits T-cell activation. ...

2016
Li Yue-Chun Chen Guang-Yi Ge Li-Sha Xing Chao Tian Xinqiao Lin Cong Dai Xiao-Ya Yang Xiangjun

To study the beneficial effects of ivabradine in dilated cardiomyopathy (DCM) mice, which evolved from coxsackievirus B3-induced chronic viral myocarditis. Four-to-five-week-old male balb/c mice were inoculated intraperitoneally with coxsackievirus B3 (Strain Nancy) on days 1, 14, and 28. The day of the first virus inoculation was defined as day 1. Thirty-five days later, the surviving chronic ...

Journal: :Journal of clinical microbiology 2013
Zhiqiang Wu Jiang Du Ting Zhang Ying Xue Fan Yang Qi Jin

Recombination events were found in two human coxsackievirus B3 strains, Beijing0811 and SD2012CHN. The strains were isolated separately from five newborns diagnosed with severe hospital-acquired acute myocarditis in Beijing in 2008 and from two children diagnosed with hand, foot, and mouth disease with concurrent acute myocarditis in Shandong in 2012.

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