background: previous studies have reported the antifertility activities of sulfonamides. this study was designed to evaluate the effects of co-trimoxazole and its co-administration with folic acid on ovarian tissue in female rats. methods: a total of 54 rats were randomly divided into 9 groups (n=6) . group i served as the control and group ii (vehicle) received saline. other groups, iii to ix,...

Oral therapies alternative to fluoroquinolones against staphylococcal chronic osteomyelitis have not been evaluated in comparative studies. Consecutive nonaxial Staphylococcus aureus chronic osteomyelitis cases were included in a comparative trial after debridement. Fifty patients were randomized: group A (n = 22) was treated with cloxacillin for 6 weeks intravenously plus 2 weeks orally (p.o.)...

Abstract Background Growth of drug resistance is related to number of microbial characteristics, selective pressure by antibiotic use and social and technical vicissitudes that enhance the transmission of antibiotic resistant organisms. The aim of this study was to investigate antimicrobial-resistance of Escherichia coli isolated from children in Shahid Sadoughi hospital of Yazd. Material...

Within the health policy field, a growing literature is attempting to understand the diverse responses of policy makers to research, and to explain why certain research findings make their way into policy while others are effectively ignored. In this paper we apply a policy analysis framework to the development of cotrimoxazole prophylaxis national policy in Malawi. Arguing that Malawi was one ...

The aim of the present study was to evaluate the effect of cotrimoxazole on the in vitro susceptibility of Coccidioides posadasii strains to antifungals. A total of 18 strains of C. posadasii isolated in Brazil were evaluated in this study. The assays were performed in accordance with the Clinical and Laboratory Standards Institute guidelines and the combinations were tested using the checkerbo...

Within the health policy field, a growing literature is attempting to understand the diverse responses of policy makers to research, and to explain why certain research findings make their way into policy while others are effectively ignored. In this paper we apply a policy analysis framework to the development of cotrimoxazole prophylaxis national policy in Malawi. Arguing that Malawi was one ...

Raquel Gonzalez and colleagues highlight an urgent need to evaluate antimalarials that can be safely administered to HIV-infected pregnant women on antiretroviral treatment and cotrimoxazole prophylaxis.

background: the treatment of human brucelosis is controversial. the purpose of this study was to search published clinical trial papers to provide a simple and effective treatment in brucellosis. methods: many studies on brucellosis treatment in a twenty- year span from 1993 to 2012 were searched in pubmed, web of science (isi), scopus, google scholar, magiran, iranmedex and sid. the studies th...