Two synthetic strategies are investigated for the preparation of water-soluble iridium-based catalysts for NMR signal amplification by reversible exchange (SABRE). In one approach, PEGylation of a variant N-heterocyclic carbene provided a novel catalyst with excellent water solubility. However, while SABRE-active in ethanol solutions, the catalyst lost activity in >50% water. In a second approa...

The effects of cosolvents on the solubility and hydration of small nonpolar solutes in solution has been investigated using a combination of molecular dynamics simulation and Widom particle insertion calculations. Results were obtained for helium, neon, argon, and methane solutes in solutions of sodium chloride, ammonium sulfate, calcium chloride, ammonium acetate, tetramethylammonium chloride,...

Supercritical carbon dioxide extraction (scCO2) is chosen to a treatment to remove lignin and to peel off outer cell wall layers to expose S2 layer of aspen wood fibres. The aim is to find an effective and environmentally friendly method to advance the fibrillation of the BCTMP pulp. The effects of the treatment are analysed by using scanning electron microscopy (SEM). The chemicals used togeth...

Aim: 1) To increase water solubility of indomethacin drug using mixed solvency approach. 2) To employ use of non toxic solubilizers for increasing solubility of a poorly water soluble drug. Study Design: Trial and error based experimental study. Place and Duration of Study: School of Pharmacy, Devi Ahilya Vishwavidyalaya, UTD, Takshashila Campus, Indore, India and College of Pharmacy, IPS Acade...

Aqueous core/polymer shell microcapsules with mononuclear and polynuclear core morphologies have been formed by internal phase separation from water-in-oil emulsions. The water-in-oil emulsions were prepared with the shell polymer dissolved in the aqueous phase by adding a low boiling point cosolvent. Subsequent removal of this cosolvent (by evaporation) leads to phase separation of the polymer...

Introduction Dense non-aqueous phase liquids (or DNAPLs) are liquids that are water immiscible and at the same time are heavier than water. When a spill occurs, these liquids can migrate into aquifers and become trapped in the pores. Some techniques proved to be efficient for the recovery of DNAPLs from the aquifers. One method is the injection of fluids through injection wells, for example, co...

Chemical chaperones (CC) are plant stress-related compounds that can stabilize protein structure in adverse environments. Modes of action are thought to involve hydrogen bonding, primarily with the solvent, and hydrophobic stabilization of the protein core. The objective of this study was to determine structure–function relationships between CC (and structurally related compounds) and thermal s...

Thermal transport in aqueous suspensions of Au-core polymer-shell nanoparticles is investigated by time-resolved measurements of optical absorption. The addition of an organic cosolvent to the suspension causes the polystyrene component of the polymer shell to swell, and this change in the microstructure of the shell increases the effective thermal conductivity of the shell by a factor of appro...