2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a by-product o f t he
trichlorophenol (herbicide) production and is also produced through a variety of
combustion processes. It appears that TCDD is a ubiquitous chemical, particularly
in industrialised countries, and the liver is the target organ of its toxicity. The
prominent hepatotoxic effect of TCDD is progressive centrilobular necrosis. Th...