S ince the introduction of corneal collagen crosslinking (CXL), this therapeutic procedure has been developed as an option for the management of keratoconus and other corneal ectatic conditions. A number of publications have assessed the safety and clinical efficacy of the procedure in the treatment of these conditions. Such studies seem to signify that CXL is a treatment that decreases the nee...

Case  Description- A  3-month-old  female  intact  Boxer  dog  was  presented  to  the  Veterinary  Hospital  of  Shahid Bahonar  University  of  Kerman  with  a  complaint  epiphora,  photophobia  and  corneal  opacity  of  both  eyes.  Clinical Findings-  Ophthalmic  examination  revealed  mild  blepharospasm  and  mucoid  discharge  of  both  eyes,  with  severe  bilateral  chemosis  and  c...

We sought to determine if connective tissue growth factor (CTGF) is necessary for the formation of corneal haze after corneal injury. Mice with post-natal, tamoxifen-induced, knockout of CTGF were subjected to excimer laser phototherapeutic keratectomy (PTK) and the corneas were allowed to heal. The extent of scaring was observed in non-induced mice, heterozygotes, and full homozygous knockout ...

PURPOSE We compared corneal backscatter estimated from a Scheimpflug camera with backscatter estimated from a clinical confocal microscope across a wide range of corneal haze. METHODS A total of 59 corneas from 35 patients with a range of severity of Fuchs' endothelial corneal dystrophy and 15 corneas from 9 normal participants were examined using a Scheimpflug camera (Pentacam) and a confoca...

PURPOSE To study, with the use of an animal model, the efficacy of amniotic membrane (AM) transplantation as adjunctive treatment in corneal healing after bacterial keratitis. METHODS Staphylococcus aureus keratitis was induced in 47 rats by injection of bacteria into the corneal stroma. Treatment was started 48 hours later with one of three randomly assigned protocols: cefazolin drops (50 mg...

A 15-year-old girl presented to our clinic with a history of gradual loss of vision and photosensitivity. She had bilateral corneal haze with stromal oedema. Her best-corrected visual acuity was 20/400 in the right eye and 20/200 in the left. She underwent penetrating keratoplasty in both eyes. Corneal histopathology revealed a pattern similar to Fuchs' endothelial dystrophy. The graft settled ...

PURPOSE To describe stromal changes after a femtosecond laser laser-assisted in situ keratomileusis (LASIK) flap was created but not separated. DESIGN Case report. METHODS As part of a randomized paired-eye study comparing LASIK flap creation by a femtosecond laser to a mechanical microkeratome, a femtosecond laser flap was successfully created on one eye of one patient, but the flap was no...

AIM To report the clinical presentation, surgical management, and outcome of retinal detachment following excimer laser. METHODS Retrospective analysis of retinal detachments observed in 11 eyes of 10 myopic patients who had previously undergone photorefractive keratectomy (PRK) or phototherapeutic keratectomy (PTK) by excimer laser. RESULTS Symptoms of visual loss in two eyes were initiall...

PURPOSE To compare the efficacy and side effects of loteprednol versus fluorometholone after myopic photorefractive keratectomy (PRK). METHODS One hundred and twenty four eyes of 62 patients who underwent PRK were enrolled in this study. One eye of each subject was randomized to receive loteprednol 0.5% and the fellow eye was given fluorometholone 0.1%. Patients were followed up for three mon...

We report a case of tectonic corneal transplantation for impending corneal perforation to preserve anatomic integrity using cryopreserved donor tissue. An 82-year-old woman exhibiting impending corneal perforation suffered from moderate ocular pain in the left eye for one week. After abnormal tissues around the impending perforation area were carefully peeled away using a Crescent blade and Van...