There is an evolution in the demands of modern ophthalmology from descriptive findings to assessment of cellular-level changes by using in vivo confocal microscopy. Confocal microscopy, by producing greyscale images, enables a microstructural insight into the in vivo cornea in both health and disease, including epithelial changes, stromal degenerative or dystrophic diseases, endothelial patholo...

This mini-review provides an overview of recent trends in our understanding of the general structure of the cornea, the importance of corneal nerves, their function and distribution in the different layers of the cornea based on reports obtained by imaging techniques such as in vivo confocal microscopy (IVCM) and immunohistochemistry (IHC) analysis. Recent data on corneal nerve status in condit...

In the present study, the effects of the acute and chronic oral administrations (po) of curcumin in the absence and presence of morphine and naloxone was investigated on the sensation of acute corneal pain in rats. Acute corneal pain was induced by the local application of hypertonic saline (5 M NaCl) on the corneal surface, and the number of eye wipes was then counted for 30 s. Subcutaneous (s...

Moraxella keratitis has been commonly described as a disease of debilitated older patients, particularly malnourished chronic alcoholics. This communication reviews the features of corneal infection due to Moraxella nonliquifaciens occurring in both young and old patients in otherwise good general health. Chronic corneal epithelial disturbance was a common finding in the 8 patients reported, in...

Acute corneal hydrops is a rare complication caused by a rupture in Descemet’s membrane as a result of progressive corneal thinning, normally due to advanced forms of corneal ectatic disorders.We report a case of unilateral pellucid marginal degeneration (PMD) which presented as acute corneal hydrops in a 56-year-old woman with no history of ocular or systemic disease. J Emmetropia 2014; 5: 43-...

purpose: to image leukocyte adherence to the vascular endothelium and extravasation into surrounding tissues in neovascularized corneas using acridine orange, a selective dna stain, in rats methods: corneal neovascularization was induced by placing two sutures in the cornea of one eye of 12 long-evans rats. one week later, acridine orange (4 mg/kg) was injected via the tail vein and the eyes we...