OBJECTIVE To compare the new delayed start protocol against the conventional gonadotropin (Gn)-releasing hormone antagonist protocol in poor responders (PORs). STUDY DESIGN A total of 160 women with poor response to previous in vitro fertilization (IVF) cycle were randomized either to start Gn then Cetrotide 0.25 subcutaneously (sc) added when leading follicle (DF) reach >12 mm or Cetrotide 0...

BACKGROUND Women with polycystic ovary syndrome (PCOS) are at risk of developing ovarian hyperstimulation syndrome (OHSS) during ovarian stimulation. Use of GnRH antagonist in the general subfertile population is associated with lower incidence of OHSS than agonists and similar probability of live birth but it is unclear if this is true for patients with PCOS. Our aim was to compare the flexibl...

OBJECTIVE To compare two short protocols for ovarian stimulation in IVF cycles using an antagonist and an agonist short protocol. The outcomes studied were dosis rec FSH needed, days of stimulation, number of oocytes retrieved and pregnancy outcome. METHODS A prospective randomised study design. INCLUSION CRITERIA first or second IVF attempt in women younger than 40 years. In the agonist pr...

In this study, we propose a new controlled ovarian hyperstimulation (COH) protocol for polycystic ovary syndrome(PCOS) that doesn’t cause hyper stimulation syndrome (OHSS) while maintaining egg quality. We also compare the conventional GnRH antagonist PCOS with COH at our hospital, and show is more secure than protocol. Eighty-seven patients of were treated in 38 49 patients. The was based on F...

the aim of this study was to evaluate the outcomes of adding low-dose hcg (human chorionic gonadotropin), as an lh active supplement, to a gnrh antagonist protocol in patients undergoing assisted reproduction techniques. in this parallel-group randomized clinical trial, 137 infertile female outpatients aged 20 - 39 years were randomized into two groups: hcg group and non-hcg group. all patients...

OBJECTIVE To review published randomized controlled trials (RCTs) evaluating the outcomes of in vitro fertilization/intra-cytoplasmic sperm injection (IVF/ICSI) utilization of gonadotropin-releasing hormone (GnRH) antagonists for ovarian stimulation in polycystic ovarian syndrome (PCOS) patients compared with classic luteal long agonist protocols. DESIGN A meta-analysis of prospective randomi...

BACKGROUND Although initial studies in poor responders using GnRH antagonists have reported encouraging results, they are limited in number, only a few of them are prospective, while the majority is characterized by limited power to detect a clinically important difference. METHODS A randomized controlled trial was performed in patients with one or more previous failed IVF cycles in which fiv...

Objective This retrospective study compared the effect of the luteal phase ovarian stimulation protocol (LP group) with the gonadotrophin-releasing hormone (GnRH) antagonist protocol (AN group) in women with poor ovarian responses. Methods Ovarian stimulation was initiated with 225 IU of human gonadotrophin (hMG) daily. When the dominant follicle diameter exceeded 13 mm, 0.25 mg of a GnRH antag...

Abstract Study question To compare the clinical outcomes and cost-efficiency between gonadotropin-releasing hormone (GnRH) antagonist progestin-primed ovarian stimulation (PPOS) protocol in high responders. Summary answer Comparing with PPOS protocol, GnRH was associated shorter time to live birth, higher OHSS rate less cost What is known already For responders prone develop hyperstimulation sy...